This library provides a comprehensive set of global and country-specific tools, guidance, and other resources to support oxygen scale-up and long-term respiratory care planning.
JOURNAL PUBLICATION | Published in Frontiers in Pediatrics, this study examined the extent to which pediatric and neonatal inpatients are monitored and treated for hypoxemia in Rwanda.
JOURNAL PUBLICATION | Published in British Journal of Anesthesia, this study hypothesized that color bias in pulse oximetry results from the optical properties of two LED sources typically used in commercial pulse oximeters.
TOOL | Open Oximetry has created a simple process to help build a custom pulse oximetry infographic.
JOURNAL PUBLICATION | Published in VeriXiv, this quasi-experimental trial found that a concentrator-based oxygen system with automated back-up reduced oxygen interruptions and transfers for hypoxemic children in western Uganda.
JOURNAL PUBLICATION | Published in the American Journal of Perinatology, this cross-sectional survey assessed Colorado and Wyoming physicians’ perceptions and practices surrounding technology in NICU graduates, particularly considering the altitude.
JOURNAL PUBLICATION | Published in medRxiv, this study analyzed the frequency of missed opportunities for hospitalization of IMCI severe pneumonia cases under the AIRE project in Burkina Faso, Guinea, Mali, and Niger.
GUIDANCE | This guidance is intended to support the development of an actionable plan for medical oxygen scale up, which should follow a clear methodology and elements for continuous monitoring and evaluating.
JOURNAL PUBLICATION | The Lancet Global Health Commission on medical oxygen security aimed to synthesize available evidence and produce actionable recommendations. This article highlights the results of the Commission’s work.
GUIDANCE | This website outlines treatment guidelines for use of oxygen after COVID-19, including mechanical insufflator-exsufflator (MIE), home ventilator treatment, and oxygen therapy at home.
JOURNAL PUBLICATION | Published in The Lancet Global Health, this case study focuses on the incorporation and expansion of pulse oximetry within the Integrated Management of Childhood Illnesses (IMCI) programme in Bangladesh.
JOURNAL PUBLICATION | Published in The Lancet Global Health, this review aimed to estimate hypoxemia prevalence for adults and children with acute illness attending health facilities in low-income and middle-income countries (LMICs).
JOURNAL PUBLICATION | Published in Annals of the American Thoracic Society, this article examines which patients require long-term oxygen therapy.
JOURNAL PUBLICATION | Published in Sensors, this study sought to further investigate the root causes of overestimation of arterial oxygen saturation (SpO2) in individuals with darker skin.
JOURNAL PUBLICATION | Published in PLoS Global Public Health, this prospective study evaluated acceptability and feasibility of a multimodal pulse oximeter used by CHWs during their iCCM of childhood illness in rural Burundi.
ARTICLE | The U.S. Food and Drug Administration published new draft guidance aimed at helping improve the accuracy and performance of pulse oximeters across the range of skin pigmentation.
JOURNAL PUBLICATION | Published in PLoS One, this study aimed to assess factors associated with oxygen administration to critically ill patients among nurses at Muhimbili National Hospital (MNH) in Dar es Salaam, Tanzania.
PRESENTATION / WEBINAR | Published by Masimo, this webinar explores the impact of skin pigmentation on pulse oximeter accuracy and introduces advanced technology solutions to improve readings across all skin tones.
JOURNAL PUBLICATION | Published in Engineering and Technology Journal, this study aims to solve the problems of most aftermarket pulse oximeters by developing a cheap, durable, easy to operate, and enhanced reflectance option.
JOURNAL PUBLICATION | Published in Universal Library of Clinical Nursing, this review reports the extent of measurement bias for pulse oximeters, describes its clinical importance, and discusses approaches to eliminating it.
JOURNAL PUBLICATION | Published in medRxiv, this study examined how healthcare workers adopted pulse oximeters and explored the contexts influencing their adoption in Burkina Faso, Guinea, Mali, and Niger under the AIRE project.
JOURNAL PUBLICATION | Published in IEEE, this study investigates the impact of melanin concentration on the accuracy of oxygen saturation (SpO2) estimation using reflective photoplethysmography (PPG) measurements.
JOURNAL PUBLICATION | Published in Pediatric Pulmonology, this study assesses families’ perceptions of consumer-grade oxygen saturation monitors, highlighting usage patterns and the need for education.
GUIDANCE | This guideline aims to help WHO Member States and their partners make evidence-informed decisions on the appropriate actions in their efforts to address common childhood illnesses, including pneumonia and diarrhea.
JOURNAL PUBLICATION | Published in Early Human Development, this paper emphasizes that the scarcity of oxygen blenders and continuous monitoring may pose a challenge in LMICs, increasing the risks of hypoxia and hyperoxia.
JOURNAL PUBLICATION | Published in CHEST Critical Care, this study examined the frequencies of pulse oximeter monitoring in operative and nonoperative contexts and the observed distribution of pulse oximeter readings.
JOURNAL PUBLICATION | Published in BMJ Global Health, this study examines whether stabilization rooms equipped with pulse oximetry and oxygen alongside HCW training improved quality of care for children with pneumonia in Nigeria.
JOURNAL PUBLICATION |
Published in BMJ Global Health, this study examines whether stabilization rooms equipped with pulse oximetry and oxygen alongside HCW training improved quality of care for children with pneumonia in Nigeria.
JOURNAL PUBLICATION | Published in Annals of the American Thoracic Society, this paper describes how this rule recognizes that pulse oximeters are less reliable on dark skin pigmentation and needs to be addressed.
JOURNAL PUBLICATION | Published in BMJ Global Health, this study examines how stabilization rooms under the INSPIRING-Lagos project improved pulse oximetry practices, for whom, and in what contexts in Nigeria.
JOURNAL PUBLICATION | Published in BMJ Global Health, this study examines how stabilization rooms under the INSPIRING-Lagos project improved pulse oximetry practices, for whom, and in what contexts in Nigeria.
JOURNAL PUBLICATION | Published in Journal of Hospital Medicine, this study found that most continuous pulse oximetry monitoring in stable bronchiolitis patients was done without clinical justification.
JOURNAL PUBLICATION | Published in The Lancet, this cluster-randomized controlled trial in India and Tanzania evaluated the effects of pulse oximetry and clinical decision support algorithms on child hospitalization and mortality.
REPORT | This report analyzes data collected during facility assessments in ten provinces across Zambia, by service ward type, to provide a snapshot of the country’s medical oxygen ecosystem.
JOURNAL PUBLICATION | Published in medRxiv, this study found that integrating pulse oximetry into IMCI consultations in West African primary health centers was generally well accepted, especially after training.
JOURNAL PUBLICATION | Published in Journal of Education and Health Promotion, this study assesses the knowledge, attitudes, and practices of resident doctors regarding oxygen therapy.
JOURNAL PUBLICATION | Published in Anesthesia & Analgesia, the meta-analysis found no significant difference in mortality or intensive care unit outcomes between patients managed with lower or higher oxygenation targets.
JOURNAL PUBLICATION | Posted on medRxiv in 2024, the study reviewed the epidemiology, pathways, patterns of care, and Day-14 mortality of severe hypoxemic cases among children under 5 in West Africa.
JOURNAL PUBLICATION | Preprint in medRxiv, this study examines the use of pulse oximetry integrated into IMCI consultations at primary healthcare centers in West Africa, identifying severe hypoxemia and related factors.
REPORT | The WHO convened a meeting in Dakar, Senegal, from May 14 to 16, 2024 to produce a template for developing evidence-based, inclusive and costed national plans for oxygen scale up.
JOURNAL PUBLICATION | Published in Journal Medical Internet Research, this study explores the impact of social media, specifically X, on increasing awareness of racial disparities in the accuracy of pulse oximetry.
JOURNAL PUBLICATION | Published in The Lancet Global Health, this study examines an intervention in Uganda aimed at improving medical oxygen services for children, resulting in better oxygen access and reduced mortality.
JOURNAL PUBLICATION | Published in PLoS One, this study aimed to assess the pooled prevalence of health professionals’ knowledge, attitude, practice, and determinant factors about oxygen therapy in Ethiopia.
JOURNAL PUBLICATION | Published in Lung India, this study determines normative values of SpO2 by pulse oximetry in apparently healthy children and to explore variation in oxygen saturation levels by age and gender.
JOURNAL PUBLICATION | Published in the African Journal of Emergency Medicine, this study assesses oxygen therapy practices and associated factors influencing oxygen administration among nurses in an Ethiopian hospital.
JOURNAL PUBLICATION | Published in World Journal of Clinical Pediatrics, this study evaluates the advantages, limitations, and challenges of pulse oximetry in clinical practice, as well as proposes recommendations to optimize its use.
JOURNAL PUBLICATION | Published in Cureus, this paper reviews the history and evolution of pulse oximeters, the scientific laws behind oximetry, and the limitations of pulse oximetry, especially related to skin pigmentation.
JOURNAL PUBLICATION | Published in The Lancet Global Health, this study re-evaluates the role of oxygen saturation levels and pulse oximetry in primary care for managing hypoxemia in children.
JOURNAL PUBLICATION | Published in The Lancet, this article presents global mortality and life expectancy data from 1950 to 2021, highlighting the impact of COVID-19 on population health.
GOVERNMENT POLICY / STRATEGY | This strategy provides a clear roadmap for increasing access to medical oxygen to reach those in need at all levels of the healthcare system in Rwanda.
JOURNAL PUBLICATION | Published in The Journal of Pediatrics, this study found that early hyperoxemia in infants with hypoxic-ischemic encephalopathy is linked to higher rates of death and major disability.
JOURNAL PUBLICATION | Published in EBioMedicine, this study evaluated eleven popular fingertip pulse oximeters using the U.S. FDA Guidance (2013) and ISO Standards (2017) in 34 humans with diverse skin pigmentation.
JOURNAL PUBLICATION | Published in the NIH Clinical Trials Registry, this study will compare high-flow and standard-flow oxygen in hypoxemic adults across five LMIC hospitals to assess mortality, oxygen use, and implementation challenges.
JOURNAL PUBLICATION | Published in The Lancet Regional Health – West Pacific, this study identified clinical predictors like reduced breath sounds as key indicators of hypoxic pneumonia in children in PNG.
JOURNAL PUBLICATION | Published in World Journal of Surgery, this study demonstrated that TIF improved trauma care and reduced mortality in Ghanaian hospitals, though regional hospitals outperformed district hospitals.
JOURNAL PUBLICATION | Published in PLoS One, this study assesses mortality risk factors in hospitalized HIV-negative children with LCWI pneumonia, recommending hospital care for those with hypoxemia, HIV exposure, or malnutrition.
JOURNAL PUBLICATION | Published in Intensive Care Medicine, the Oxy-PICU trial found no significant differences in clinical outcomes between conservative and liberal oxygenation targets for critically ill children.
GUIDANCE | This document provides an evidence-based strategy for chronic obstructive pulmonary disease (COPD) diagnosis, management, and prevention, with citations from the scientific literature.
JOURNAL PUBLICATION | Published in the Journal of Global Health, this study used the Lives Saved Tool to prospectively analyze the potential impact of upscaling pneumonia interventions in Bangladesh, Chad, and Ethiopia.
GUIDANCE | This manual includes the systematic approach to a cardiopulmonary emergency, effective team communication, and the ACLS cases and algorithms.
JOURNAL PUBLICATION | Published in The Lancet Global Health, this article discusses how AI is revolutionizing pneumonia diagnosis and management through deep-learning applications in medical imaging and lung sound analysis.
JOURNAL PUBLICATION | Published in Global Surgery, this conference abstract presents the results of a survey of perioperative safety practices at secondary and tertiary facilities in Plateau State, Nigeria.
JOURNAL PUBLICATION | Published in BMJ Global Health, this article analyzes the impact of the COVID-19 pandemic on hospital care for critical illness in low-resource settings and provides recommendations for future improvements.
JOURNAL PUBLICATION | Published in Paedetrics & Child Health, this prospective study looked at SpO2 measurements in healthy neonates admitted to postnatal wards and followed up in Calgary, Alberta, Canada.
JOURNAL PUBLICATION | Published in BMC Ophthalmology, this cross-sectional study of preterm infants from the neonatal units of two Ugandan hospitals examined retinopathy of prematurity (ROP).
JOURNAL PUBLICATION | Published in The Lancet Global Health, this study makes the case for oxygen saturation (SpO2) measured by pulse oximetry as an essential fifth vital sign in all sick children.
JOURNAL PUBLICATION | Published in Frontiers in Pediatrics, this study developed and validated clinical models to identify hypoxemic pneumonia in children without pulse oximeters in low-resource settings.
JOURNAL PUBLICATION | Published in PLoS Digital Health, this article investigates how digital determinants of health contribute to bias in health technologies and their potential impact on healthcare equity.
JOURNAL PUBLICATION | Published in The Lancet, this study provides global, regional, and national estimates of preterm birth rates for 2020, highlighting trends since 2010 and calling for targeted interventions.
JOURNAL PUBLICATION | Published in ERJ Open Research, this systematic review summarizes the existing evidence for SpO2 thresholds in children with respiratory distress.
JOURNAL PUBLICATION | Published in The International Journal of Tuberculosis and Lung Disease, this consensus-based study provides clinical standards for managing asthma in LMICs, covering diagnosis, treatment, and emergencies.
JOURNAL PUBLICATION | Published in The Lancet Respiratory Medicine, this article calls for a revision of WHO’s pneumonia guidelines in light of new findings from Bangladesh.
JOURNAL PUBLICATION | Published in Frontiers in Pediatrics, this study assessed predictors of critical care needs and hospital mortality in South African children with COVID-19 infection in a region with high HIV burden.
JOURNAL PUBLICATION | Published in BMJ Open, this study examined the prevalence and phenotypic trajectories of hypoxemia among hospitalized adults in Kenya, with a focus on chronic hypoxemia.
JOURNAL PUBLICATION | Published in Journal of Global Health, this review describes the landscape of pulse oximetry training for health workers in LMICs prior to the COVID-19 pandemic, as described in the literature.
JOURNAL PUBLICATION | Published in The Lancet Respiratory Medicine, this study sought to establish the outpatient burden, mortality risk, and prognostic accuracy of death from hypoxemia in children with suspected pneumonia in Bangladesh.
JOURNAL PUBLICATION | Published in BMC Health Services Research, this review explored the acceptability of health technology innovations in sub-Saharan Africa, revealing a lack of consistent frameworks.
JOURNAL PUBLICATION | Published in BMC Emergency Medicine, this study highlights that over 10% of patients at a Tanzanian hospital’s ED were critically ill, with respiratory and cardiovascular issues being the primary causes.
JOURNAL PUBLICATION | Published in EClinicalMedicine, this study describes adherence to WHO recommendations for the management of leading causes of death among children across a number of LMICs.
JOURNAL PUBLICATION | Each year this booklet is compiled to summarize the evidence on child and adolescent health derived from randomized or controlled trials in developing countries over the previous year.
JOURNAL PUBLICATION | Published in PLoS Global Public Health, this study explores the usability of pulse oximeters for community health and primary care workers in Cambodia, Ethiopia, South Sudan, and Uganda.
JOURNAL PUBLICATION | In this second part in NEJM Evidence, we discuss the acute and chronic indications for oxygen, the delivery of supplemental oxygen, and its potential adverse effects and toxicity.
TOOL | This publication was developed in response to the need for a reference list of priority medical devices required for management of noncommunicable diseases (NCDs), focusing on cardiovascular diseases and diabetes.
JOURNAL PUBLICATION | Published in the American Journal of Respiratory and Critical Care Medicine, this study presents a pooled analysis of four IMCI-related models predicting SpO2 <93% (primary) and <90% (secondary).
JOURNAL PUBLICATION | Published in Opportunities and Advances in Pediatric Global Health, this study evaluates the diagnostic performance of a SpO2 measurement as a test for radiographic pneumonia in children in Bangladesh.
JOURNAL PUBLICATION | Published in the American Journal of Epidemiology, this study analyzed pulse oximeter accuracy on darker skin pigmentation and its association with COVID-19 treatment outcomes in Northern California.
JOURNAL PUBLICATION | Published in International Journal of Infectious Diseases, this study evaluates the role of pulse oximetry in improving pneumonia risk stratification and patient outcomes in children under 5 years.
GOVERNMENT POLICY / STRATEGY | This second national strategy builds on the foundations laid by the first plan (2017-2022) for more equitable access to medical oxygen in health facilities in Nigeria.
JOURNAL PUBLICATION | Published in Frontiers in Medicine, this literature review and analysis considered SpO2 targets used in previous trials, international and national society guidelines, and direct trial evidence.
JOURNAL PUBLICATION | In part I of a two-part review in NEJM Evidence, Wemple and colleagues discuss the physiology of tissue hypoxia, mechanisms of hypoxemia, and its clinical assessment.
JOURNAL PUBLICATION | Published in Sensors, this article describes a basic model of measurement uncertainty that specifies the factors that may degrade the accuracy of an observed measurement value from a clinical sensor.
JOURNAL PUBLICATION | Published in PLoS Global Public Health, this study created a newborn clinical audit tool and implementation guide using a human-centered design approach.
JOURNAL PUBLICATION | Published in Cost Effectiveness and Resource Allocation, the study reviewed the costs of EECC and advanced critical care in Tanzania and Kenya, highlighting its cost-effectiveness in low-resource settings.
JOURNAL PUBLICATION | Published in Current Opinion in Critical Care, this review explores the role of home oxygen monitoring during the COVID-19 pandemic, analyzing its effectiveness, cost implications, and potential equity concerns.
JOURNAL PUBLICATION | Published in JAMA, this Viewpoint discusses how some pulse oximeters can provide incorrect oxygen saturation data for dark-skinned patients compared with light-skinned patients.
JOURNAL PUBLICATION | Published in Pneumonia (Nathan Qld.), this review looks at past pulse oximetry implementation attempts in LMICs and proposes barriers and solutions for integration in the health system.
JOURNAL PUBLICATION | Published in Journal of Clinical Medicine, this paper describes specific features associated with various retinopathy of prematurity presentations.
REPOSITORY / TOOLKIT | This toolkit provides key clinical resources for physicians, covering topics from ARDS in adults, to pneumonia and from oxygen therapy and mechanical ventilation to other areas of respiratory care.
GUIDANCE | The WHO COVID-19 Clinical management: living guidance contains the Organization’s most up-to-date recommendations for the clinical management of people with COVID-19.
GOVERNMENT POLICY / STRATEGY | This strategic action plan goes into detail on the strategic framework, as outlined by the National Medical Oxygen Policy, and lays the foundation for scaling up medical oxygen across Ghana.
JOURNAL PUBLICATION | Published in the European Respiratory Journal, this study explores the changes and challenges in home oxygen therapy practices before, during, and after the COVID-19 pandemic.
JOURNAL PUBLICATION | Published in Neonatology, this study compares pulse oxygen saturation for neonates at different altitudes in China to establish cutoff values identifying hypoxemia between 30 and 120 min after birth.
JOURNAL PUBLICATION | Published in PLoS Digital Health, this study reviewed the development of ePOCT+ and the medAL-suite, emphasizing their role in improving pediatric outpatient care in LMICs.
JOURNAL PUBLICATION | Published in Current Medical Research and Opinion, this cost-effectiveness analysis compares two SpO2 thresholds for discharging infants with viral bronchiolitis from the hospital.
JOURNAL PUBLICATION | Published in Advances in Medical Education and Practice, this study highlights gaps in knowledge of acute oxygen therapy among doctors and nurses in Nigeria, pointing out significant delivery barriers.
JOURNAL PUBLICATION | Published in BMC Health Services Research, this study assesses the implementation of pulse oximeters in IMCI guidelines at PHC level in West Africa, identifying key challenges and insights.
JOURNAL PUBLICATION | Published in BMJ Open, this study describes the prevalence and clinical course of patients hospitalized with COVID-19 in Canada based on oxygenation and pneumonia status at presentation.
ARTICLE | Published in Respiratory Care, this editorial responds to findings from a recent publication and offers mitigation strategies so the use of pulse oximetry is safe for all patients.
JOURNAL PUBLICATION | Published in The Lancet Global Health, this article introduces The Lancet Global Health Commission on Medical Oxygen Security, which seeks to close critical gaps in oxygen access, especially in LMICs.
COURSE / TRAINING VIDEO | This course aims to improve the planning and management of medical oxygen and to strengthen the rational, sustainable, and safe use of medical oxygen across the Americas.
REPOSITORY / TOOLKIT | This toolkit provides trusted nursing knowledge sourced directly from professional practice organizations, regulatory, accreditation, and best practice guidelines.
ARTICLE | This article outlines key questions related to pneumonia and its treatment and key solutions to reduce morbidity and mortality from pneumonia in children.
PRESENTATION / WEBINAR | This webinar series features 11 learning hubs across Sub-Saharan Africa and Latin America, focused on oxygen therapy and critical care medicine in the context of COVID-19.
REPORT | IVAC’s annual Pneumonia and Diarrhea Progress Report evaluates the progress across 10 high-impact indicators outlined in the Global Action Plan for the Prevention and Control of Pneumonia and Diarrhea (GAPPD).
GUIDANCE | The U.S. Food and Drug Administration (FDA) is informing patients and healthcare providers that pulse oximeters have limitations and a risk of inaccuracy under certain circumstances.
JOURNAL PUBLICATION | Published in The Lancet Respiratory Medicine, this article looks at pulse oximetry-based indices as an alternative for the diagnosis and risk stratification of patients with ARDS.
GUIDANCE | The WHO guidelines for malaria provide the clinical recommendations for severe malaria cases, including when and how to administer medical oxygen.
JOURNAL PUBLICATION | Published in PLoS Global Public Health, this article examines neonatal data quality and prescribing accuracy in Kenyan hospitals, aiming to improve care monitoring for neonates.
JOURNAL PUBLICATION | Published in Paediatric Anaesthesia, this study assesses the incidence and characteristics of the detected errors in a modified WHO surgical safety list at a children’s hospital in Germany.
JOURNAL PUBLICATION | Published in Tropical Medicine & International Health, this study evaluates the cost-effectiveness of adding pulse oximetry to primary care for acute respiratory infection management in rural Thailand.
JOURNAL PUBLICATION | Published in BMJ Paediatrics Open, this study aimed to estimate the point prevalence of pneumonia and malnutrition and explore associations with household socioeconomic factors in Jigawa state, Nigeria.
JOURNAL PUBLICATION | In this article published in Nature, two groups of researchers analyze skin pigmentation’s impact on pulse oximetry readings and its effects on people with dark skin.
JOURNAL PUBLICATION | Published in Ghana Medical Journal, this study examines selected health interventions in Nigeria considered significant both in terms of COVID-19 responses and in strengthening the overall health system.
JOURNAL PUBLICATION | The study, published in Pediatrics, found that emergency department-initiated home oxygen therapy for viral bronchiolitis is a safe and cost-effective alternative to hospitalization.
JOURNAL PUBLICATION | Published in Infection and Drug Resistance, this review aimed to summarize information on the prevalence, risk factors, and outcomes of patients with happy hypoxia to improve their management.
JOURNAL PUBLICATION | Published in Pediatrics, this update provides a comprehensive review of pathophysiology, classification, diagnosis, global screening, and treatment of retinopathy of prematurity.
JOURNAL PUBLICATION | Published in Open Journal of Respiratory Diseases, this study found that oxygen therapy prescriptions in a South African hospital were frequently incomplete, with only 27% of patients having a prescription.
JOURNAL PUBLICATION | Published in BMJ Global Health, this study found that the Nigeria Oxygen Implementation programme improved hospital oxygen systems and pulse oximetry coverage, demonstrating sustainability over time.
GUIDANCE | This step-by-step guide is intended to provide a portable and practical summary of the up-to-date global evidence for newborn care focusing on the first hours and days of life.
JOURNAL PUBLICATION | Published in BMC Medicine, this study systematically reviewed the effects of skin pigmentation on the SpO2 accuracy by pulse oximetry compared with the gold standard SaO2 measured by CO-oximetry.
GUIDANCE | These guidelines outline a public health response for five key populations and discuss new recommendations and guidance from current WHO guidelines.
JOURNAL PUBLICATION | Published in PLoS Global Public Health, this study demonstrated that adding pulse oximetry to the IMCI guidelines improved the diagnosis of severe pneumonia in children but increased the cost.
GUIDANCE | This strategy aims to increase awareness about asthma and provide a mechanism to translate scientific evidence into improved asthma care worldwide.
COURSE / TRAINING VIDEO | The Training of Trainers module is meant for providing training to those participants who are expected to effectively oversee the oxygen ecosystem at their respective levels.
REPOSITORY / TOOLKIT | In order to build capacity for long-term sustainability, PATH developed, translated, and disseminated high-quality, reliable, and ready-reference knowledge products specific to India.
JOURNAL PUBLICATION | Published in SAS Journal of Medicine, this study determines the clinical predictors of hypoxemia in children with WHO defined pneumonia aged 2 to 59 months in a Bangladeshi hospital.
JOURNAL PUBLICATION | Published in Value in Health, this study assesses the cost-utility of remote pulse-oximetry monitoring of moderately ill patients with COVID-19 in the United States.
JOURNAL PUBLICATION | Published in World Journal of Surgery, this study found that initial trauma assessments at Ghanaian hospitals were well performed, but key evaluations like oxygen saturation were frequently missed.
JOURNAL PUBLICATION | Published in BMJ Open, this study evaluates factors influencing hospital length of stay in patients with suspected malaria in Kenya, emphasizing the need for early recognition and severe malaria management.
JOURNAL PUBLICATION | This study – published in Immunology and Inflammation – examined a panel of nanosensors that detect the dysregulated activity of pulmonary host proteases implicated in the response to pneumonia-causing pathogens.
JOURNAL PUBLICATION | Published in BMJ Open, this study analyzes the indirect impacts of COVID-19 on neonatal care in Zimbabwe and Malawi, highlighting changes in patient outcomes and resource availability.
JOURNAL PUBLICATION | Published in EClinicalMedicine, this study evaluates the implementation of pulse oximetry in rural Bangladesh to improve the management of childhood pneumonia.
INFORMATION BRIEF | This success story details the need, process, and mechanisms of developing a standardized oxygen ecosystem learning resource package for trainers.
COURSE / TRAINING VIDEO | This course covers pulse oximetry use in the time of COVID-19.
JOURNAL PUBLICATION | Published in BMC Health Services Research, this study highlights the positive outcomes of decentralizing oxygen services in Ethiopia’s health centers.
JOURNAL PUBLICATION | Published in The Lancet Child and Adolescent Health, the Tshwane Maternal-Child COVID-19 study investigated clinical manifestations and outcomes of pediatric patients in South Africa during the 4th wave of COVID-19.
JOURNAL PUBLICATION | Published in the Bulletin for the World Health Organization, this study investigates survival in children referred from primary care in Malawi, with a focus on hypoglycemia and hypoxemia progression.
JOURNAL PUBLICATION | Published in BMJ Open, this evaluation determines whether stabilization rooms equipped with pulse oximetry and oxygen alongside health worker training improves quality of care for children with pneumonia.
JOURNAL PUBLICATION | Published in JAMA Network, this journal article investigated whether there is differential inaccuracy of pulse oximetry by race or ethnicity among patients with COVID-19.
JOURNAL PUBLICATION | Published in Lung India, this retrospective study looked at the presence of hypoxia without dyspnea in patients with SARS-CoV-2 infection.
GUIDANCE | These consolidated guidelines inform health care professionals in Member States on how to improve treatment and care for patients with drug susceptible TB (DS-TB).
JOURNAL PUBLICATION | Published in Anesthesia & Analgesia, this study found a significantly higher incidence of severe anesthetic-related critical incidents in South African pediatric surgeries compared to high-income countries.
JOURNAL PUBLICATION | Published in Ophthalmic Epidemiology, this study shows that retinopathy of prematurity (ROP) is becoming a significant and increasing cause of childhood blindness in sub-Saharan Africa.
JOURNAL PUBLICATION | Published in BMJ Open, this observational study found that a one-day offsite training for respiratory care in Lesotho resulted in significant knowledge improvement among healthcare workers.
REPOSITORY / TOOLKIT | First published in 2020, this toolkit is intended for clinicians working in acute care, managing adult and pediatric patients with acute respiratory infection.
JOURNAL PUBLICATION | Published in PLOS Global Public Health, this study assessed the prevalence and management of hypoxemia at primary care facilities in Uganda.
JOURNAL PUBLICATION | Published in Journal of Global Health, this article explores the integration of pulse oximetry into IMCI services in Bangladesh to improve pneumonia management through stakeholder-driven policy and programme development.
JOURNAL PUBLICATION | Published in Journal of Global Health, this study assesses the coverage and quality of supportive care for neonatal infections across multiple countries, identifying gaps in care and suggesting improvements.
GUIDANCE | This NEST-ED Clinical Module has been prepared to help healthcare staff and students understand when and how to use pulse oximeters in newborn care.
JOURNAL PUBLICATION | Published in Sensors (Basel, Switzerland), this review aims to study the literature that assesses the influence of skin pigmentation on the accuracy of pulse oximeters.
JOURNAL PUBLICATION | Published in Journal of Global Health, this study assessed pulse oximetry performance of different types of assessors in inpatient settings after an update to the existing IMCI package in Bangladesh.
JOURNAL PUBLICATION | Published in Annals of Medicine and Surgery, this study found that only 47% of nurses practiced oxygen therapy effectively in critically ill patients, with age and knowledge positively influencing practice.
JOURNAL PUBLICATION | Published in Humanities and Social Sciences Communications, this study evaluates the role of science advice during the COVID-19 pandemic in Sweden..
JOURNAL PUBLICATION | Published in PLoS One, this study assesses risk factors for community-acquired severe pneumonia in children under five in Bangladesh, identifying key factors such as male sex, fever, and severe stunting.
GUIDANCE | This document offers a framework that healthcare workers can use to navigate their healthcare system and serves as a guide to connect COVID-19 patients to equitable care, including oxygen therapy.
COURSE / TRAINING VIDEO | WHO has developed training videos on use of respiratory equipment, for every step of the process. This training video focuses on how to clinically use pulse oximeters.
JOURNAL PUBLICATION | Published in Journal of Indian Society of Remote Sensing, this study introduces a Geo-ICT framework to curb COVID-19 spread in India, using geo-spatial technologies for real-time data and citizen alerts.
GUIDANCE | To promote the rational use of oxygen, a set of guidelines has been put together for the development of an efficient management system to deal with situations of oxygen scarcity.
TOOL | Lifebox has worked with its global network of partners to distribute pulse oximeters across 53 countries for the ongoing care of COVID-19 patients as well as developed multi-language educational materials.
JOURNAL PUBLICATION | Published in The British Journal of General Practice, this article discusses the factors that can lead to inaccurate SpO2 readings and its implications for general practitioners and patients.
TOOL | This pocket reference provides a quick reference on respiratory care, including oxygen sources and delivery devices, respiratory mechanics, volume and pressure control, etc.
ARTICLE | In 2016, the Ethiopian Ministry of Health designed and implemented an oxygen and pulse oximetry scale up road map, which resulted in significant improvements in oxygen availability and use.
JOURNAL PUBLICATION | Published in Trials, this protocol describes the INSPIRING trial, which aims to reduce childhood pneumonia and infectious diseases in Jigawa, Nigeria, through system-wide health interventions.
GUIDANCE | These revised comprehensive guidelines outline the appropriate measures and treatment for the management of COVID-19 in children and adolescents below the age of 18 years.
GOVERNMENT POLICY / STRATEGY | The objective of this Oxygen Preparedness Plan is to identify and implement priority activities which urgently need to be undertaken to respond to the current COVID-19 outbreak in Cambodia.
ARTICLE | PATH partnered with the Malawi Ministry of Health and UNICEF to develop and launch a roadmap to establish and maintain a comprehensive national medical oxygen ecosystem.
GOVERNMENT POLICY / STRATEGY | This oxygen roadmap provides a structured and attainable plan to establish and maintain a comprehensive national medical oxygen ecosystem in Malawi.
JOURNAL PUBLICATION | Published in BMJ, this article reviews current knowledge on the management of pneumonia in critically ill patients, including community-acquired and hospital-acquired pneumonia.
GUIDANCE | Newborn Essential Solutions and Technologies-Education (NEST-ED) Clinical Modules provide educational support for each of the technologies included in the NEST360° bundle for newborn care.
JOURNAL PUBLICATION | Published in Archives of Disease in Childhood, this study determined reference values for SpO2 among healthy children under five living at moderately high altitude in Papua New Guinea.
JOURNAL PUBLICATION | Published in Journal of Hospital Medicine, this study examined continuous pulse oximetry monitoring of hospitalized infants with bronchiolitis who are not receiving supplemental oxygen.
JOURNAL PUBLICATION | Published in Autonomic Neuroscience, this study identifies silent hypoxemia and highlights predictors such as new-onset headache and early medical attention.
JOURNAL PUBLICATION | Published in BMJ Open Respiratory Research, this study found that the SpO2 threshold for hypoxemia in well children from Bangladesh was higher than the conventional <90%.
JOURNAL PUBLICATION | Published in Clinical Medical Insights: Pediatrics, this study examined the use of multimodal pulse oximeters integrated with routine OPD of primary health centers after an abridged IMNCI training.
JOURNAL PUBLICATION | This article proposes five priority areas for the research community and actionable changes to current regulations that will help improve oximeter accuracy and help reduce bias in pulse oximeter performance.
COURSE / TRAINING VIDEO | This forum focuses on teaching critical care topics followed by an open discussion for early career professionals and non-ICU trained healthcare providers.
JOURNAL PUBLICATION | Published in BMC Pediatrics, this study evaluates whether availability of oxygen and its clinical practice in public hospitals of Ethiopia changed during the time of their oxygen roadmap implementation.
GUIDANCE | This guidebook presents a comprehensive view at the entire oxygen ecosystem in Meghalaya, India and will be helpful to various stakeholders in the field.
GOVERNMENT POLICY / STRATEGY | This roadmap is intended to guide implementation and coordination of oxygen activities in Liberia, to provide cost estimates for implementation, and to support resource mobilization efforts.
GUIDANCE | These updated guidelines place an increased emphasis on improving care for sepsis patients after they are discharged from the ICU and represent greater geographic and gender diversity than previous versions.
JOURNAL PUBLICATION | Published in Operations Management Research, this study provides guidance on health supply chains during a pandemic by proposing a location-allocation model for the locations of temporary testing laboratories.
JOURNAL PUBLICATION | Published in BMJ Global Health, this study aimed to specify the content of EECC and additionally the essential diagnosis-specific care for critically ill patients with COVID-19.
JOURNAL PUBLICATION | Published in BMJ Open, this trial protocol investigates the role of pulse oximetry in improving hospital referral rates for Pakistani children under 5 with severe pneumonia.
GUIDANCE | COVIDprotocols.org was launched to create open access adaptable protocols for the management of COVID-19 patients, including in low-resource settings.
INFORMATION BRIEF | This narrative highlights the successful initiatives to equip 62 CHFs with the knowledge and skills needed to manage existing critical care patients and prepare for future health emergencies.
TOOL | This clinical job aid from NEST360 provides an overview of a Bistos pulse oximeter, including assessment and preparation as well as repair and maintenance of the device.
TOOL | This clinical job aid from NEST360 provides an overview of a LifeBox pulse oximeter, including assessment and preparation as well as repair and maintenance of the device.
JOURNAL PUBLICATION | Published in International Journal of Infectious Diseases, this study from West Africa found that COVID-19 mortality is influenced by factors like age, gender, and chronic hypertension.
GUIDANCE | These consolidated guidelines on HIV prevention, testing, treatment, service delivery and monitoring bring together existing and new clinical and programmatic recommendations across different ages, populations and settings.
JOURNAL PUBLICATION | Published in PLOS One, this study evaluates the effect of improved hospital oxygen systems on quality of care for children with severe pneumonia, severe malaria, and diarrhea with severe dehydration.
JOURNAL PUBLICATION | Published in eClinical Medicine, this study evaluated the performance of different types of pulse oximeters amongst frontline health workers in Cambodia, Ethiopia, South Sudan, and Uganda.
JOURNAL PUBLICATION | Published in BMJ Open Quality, this study reduced oxygen consumption in the special newborn care units from 8 to 4 cylinders per day, by rationalizing indications, monitoring, and delivery method.
TOOL | This document, featuring an algorithm to assess adult oxygen therapy escalation, is part of a set of tools that can be locally modified to train health providers in respiratory care.
TOOL | This document, featuring an algorithm to assess neonatal oxygen therapy escalation, is part of a set of tools that can be locally modified to train health providers in respiratory care.
TOOL | This document, featuring an algorithm to assess oxygen therapy escalation, is part of a set of tools that can be locally modified to train health providers in respiratory care.
TOOL | This document, featuring an algorithm to assess pediatric oxygen therapy escalation, is part of a set of tools that can be locally modified to train health providers in respiratory care.
JOURNAL PUBLICATION | The members of Pneumo-Strategy Group support the call to stringent regulatory agencies to immediately review the accuracy of pulse oximeters in different populations.
JOURNAL PUBLICATION | Published in Intensive Care Medicine, the COAST trial, conducted in Uganda and Kenya, compared humidified HFNT and standard low-flow nasal oxygen in children with severe hypoxemia.
JOURNAL PUBLICATION | Published in Tropical Medicine & International Health, this study evaluates neonatal mortality in rural northern Ghana, applying the Three Delays Model to understand contributing factors.
JOURNAL PUBLICATION | Published in the Journal of Applied Physiology, this review examined, through multiple databases, the first appearance of “hypoxia” and related terms “hypoxemia” and “hypoxybiosis” in scientific literature.
GUIDANCE | This is a guidance document to support the use of pulse oximeter for assessment of suspected and confirmed cases of COVID-19 in the community.
JOURNAL PUBLICATION | Published in Acta Paediatrica, this study identifies whether Ethiopia’s health extension workers adhere to required guidelines while assessing children under 5 with cough or difficulty breathing.
JOURNAL PUBLICATION | Published in Hospital Practice, this study found that oxygen therapy in a tertiary hospital was often administered without proper orders, leading to widespread hyperoxia and potential patient harm.
GUIDANCE | The NEST-ED Technical Modules help technical staff and students understand the basics of when and how to use equipment essential to newborn care, such as pulse oximeters.
JOURNAL PUBLICATION | Published in Neonatology, this review looked at FiO2 and how it should be changed to reach an optimal SpO2 measured by pulse oximetry target within the first 5-10 min of...
TOOL | This tool is meant to support the strengthening of oxygen ecosystems, including infrastructure design and maintenance, supply chain, training and ongoing mentorship, and clinical guideline development.
GUIDANCE | This NEST-ED Clinical Module has been prepared to help healthcare staff and students understand when and how to use oxygen therapy in newborn care.
JOURNAL PUBLICATION | Published in Journal of Biosciences and Medicines, this article explores the occurrence of “happy hypoxia” in COVID-19 patients in Kinshasa, highlighting the importance of early detection.
GUIDANCE | This resource aggregates guidelines for COVID-19 care from leading global health authorities and consolidates them into a single recommendation based on concordance.
GUIDANCE | This manual is intended for healthcare providers in Malawi to identify and provide appropriate care for patients with acute respiratory infection when COVID-19 is suspected.
JOURNAL PUBLICATION | Published in Journal of Global Health, this article highlights the importance of pulse oximetry in detecting “silent hypoxemia” and managing COVID-19 patients outside hospital settings.
GUIDANCE | This COVIDprotocols.org section on oxygen care outlines treatment options in patients, both invasive and noninvasive ventilation.
GUIDANCE | COVIDprotocols.org was launched to create open access adaptable protocols for the management of COVID-19 patients, including guidelines focused on COVID-19 care in resource-limited settings.
JOURNAL PUBLICATION | As highlighted in this Global Health: Science and Practice article, field experience from African and Asia-Pacific contexts reveal practical strategies whereby hospitals can rapidly improve their oxygen systems.
GUIDANCE | This guideline is focused on improving the quality of care for severely ill children – describing detection of hypoxemia, use of pulse oximetry, oxygen delivery system, etc.
JOURNAL PUBLICATION | Published in Archives of Disease in Childhood, this study examines admissions for bronchiolitis, comparing centers in the U.K. with oxygen saturation thresholds for admission of 90% versus 92%.
JOURNAL PUBLICATION | Published in Resuscitation Plus, this study examined the variables associated with the decision to provide supplemental oxygen made by emergency department staff, without access to oximetry, in a Ugandan hospital.
JOURNAL PUBLICATION | This study analyzed paired pulse oximetry measures of oxygen saturation and measures of arterial oxygen saturation and compared the results to patients who identified themselves as White or Black.
ARTICLE | This presentation outlines Lao PDR’s COVID-19 response, focusing on data systems for case tracking, hospital capacity management, and the use of technology to monitor oxygen availability.
JOURNAL PUBLICATION | Published in PLoS One, this study assesses the impact of portable pulse oximeters and IMCI continued education on the diagnosis and treatment of fever among pediatric patients in rural Malawi.
GUIDANCE | This collection of resources provides an evidence-based model for sustainable, high-quality hospital-based newborn care in limited-resource settings, including respiratory care and oxygen therapy.
JOURNAL PUBLICATION | Published in PLOS Med, this study determined mortality outcomes of infants and children diagnosed and referred using clinical guidelines with or without pulse oximetry in Malawi.
JOURNAL PUBLICATION | As highlighted in this CHEST Journal article, the COVID-19 pandemic has revealed just how unprepared most countries have been to deal with widescale, rapidly increasing outbreaks of viral pneumonia.
JOURNAL PUBLICATION | This article in the Bulletin of the World Health Organization outlines key gaps and challenges around providing medical oxygen to patients who need it.
JOURNAL PUBLICATION | Published in BMJ Open, this study, a first of its kind, will identify newborn signal functions in Bangladesh on which newborn service availability at a health facility can be assessed.
GUIDANCE | This document describes the procedures for ensuring health facilities are properly equipped to manage patient care during the COVID-19 pandemic.
REPOSITORY / TOOLKIT | This catalogue provides a comprehensive list of training resources aimed to better equip healthcare workers in LMICs who are directly involved in patient care to address the COVID-19 pandemic.
GUIDANCE | This guidance document provides key information on the clinical management of COVID-19 acute respiratory disease, including case definition, modes of transmission, and diagnosis, and treatment protocols.
GUIDANCE | The purpose of this document is to provide clinical guidance to clinicians working in a low-resource setting during the COVID-19 pandemic.
GUIDANCE | Published by the World Health Organization, this guidance document provides recommendations for safe home care of COVID-19 patients with mild symptoms and management of their contacts.
JOURNAL PUBLICATION | This article in the journal Antibiotics talks about patients with pneumonia and other respiratory diseases in hospital settings.
REPORT | The Every Newborn Action Plans provides a roadmap to end preventable newborn mortality, reduce disability, and end preventable stillbirths by 2030.
TOOL | This card provides a summary tool on respiratory therapy, but is not a substitute for clinical decision making based on the medical condition presented.
GUIDANCE | This rapid advice guide examines the evidence and makes recommendations for the use of chest imaging in acute care of adult patients with suspected, probable, or confirmed COVID-19.
PRESENTATION / WEBINAR | WHO and IFMBE Clinical Engineering Division partnered to host a series of COVID-19 Critical Topic 1-hour webinars during May 2020.
JOURNAL PUBLICATION | Published in Mayo Clinic Proceedings, this study aimed to identify markers associated with in-hospital death in patients with coronavirus disease 2019 (COVID-19)-associated pneumonia in Wuhan, China.
JOURNAL PUBLICATION | Published in Anesthesia & Analgesia, this study found caregiver and community perceptions of pneumonia in Nigeria are influenced by limited knowledge of symptoms, family dynamics, and cost barriers.
GOVERNMENT POLICY / STRATEGY | The purpose of this document is to re-commence and maintain non-COVID-19 essential services, which were halted during the COVID-19 epidemic response in health facilities, across Ethiopia.
JOURNAL PUBLICATION | Published in Pediatric Pulmonology, this article discusses the implementation of improved oxygen systems in Nigerian hospitals and their impact on reducing child mortality due to pneumonia.
GOVERNMENT POLICY / STRATEGY | This document provides the framework for preparation and implementation of the Emergency COVID Response Plan (ECRP) with details of activities necessary for effective emergency response across India.
JOURNAL PUBLICATION | Published in International Journal of Pharmaceutical Sciences and Research, this article describes COVID-19 response strategies that were developed and adopted by a large, multispecialty hospital in India.
JOURNAL PUBLICATION | Published in BMJ Open, this study aimed to assess whether pulse oximetry improves health workers’ performance in diagnosing severe childhood pneumonia at health centres in Southern Ethiopia.
JOURNAL PUBLICATION | Published in Geocarto International, this article reports a COVID-19 management strategy from India, using an integrated satellite remote sensing, GIS, and local knowledge-based approach.
GUIDANCE | This case management manual is intended to guide clinical care of patients with COVID-19 in Malawi. It is the first edition.
GUIDANCE | This tutorial provides a quick reference on the clinical signs of severe COVID-19, when to give oxygen, which methods can be used, and other considerations related to its delivery.
GUIDANCE | The purpose of this review is to present COVID-19-related questions in emergency medicine as pertains to the South African context.
REPOSITORY / TOOLKIT | This set of resources includes various oxygen and pulse oximetry trainings and tools collated by Dr. Hamish Graham.
GUIDANCE | The purpose of this document is to provide guidelines for setting up of quarantine facilities during the COVID-19 pandemic.
GUIDANCE | The document provides guidelines for setting up isolation facilities for COVID-19 patients at district hospitals in India.
GUIDANCE | This document provides clinicians with updated interim guidance on timely, effective, and safe supportive management of patients with COVID-19 and severe acute respiratory infection.
GUIDANCE | Published by the Department of Health, Philippines, this document outlines urgent measures to enhance case investigation and contact tracing, including the formation of COVID-19 Special Teams for regional response.
GUIDANCE | These interim guidelines and protocols for SARS-CoV-2 and COVID-19 combine both preventive and clinical management of the disease in the Kenyan context.
PRESENTATION / WEBINAR | This presentation provides an introduction to oxygen delivery devices, including general terminology, high-flow vs. low-flow, the various oxygen sources, consumption tracking, delivery devices, and more.
REPORT | This joint report focuses on the world’s most vulnerable: outlines the global problem, emphasizes progress made, and summarizes what can be done to transform care for small and sick newborns.
GUIDANCE | This document aims to provide clinical guidance on palliative care during the COVID-19 pandemic, specifically for use in low-resource settings.
GUIDANCE | This consensus statement provides clarity on airway management for COVID-19 patients and where that guidance differs for pediatric patients.
COURSE / TRAINING VIDEO | This is an instructional video to show the use of a LifeBox pulse oximeter in the context of the COVID-19 pandemic.
JOURNAL PUBLICATION | From an urgent and pragmatic perspective, this article published in BMC Critical Care suggests creative uses of existing resources and repurposing others for human medical care.
JOURNAL PUBLICATION | Published in Early Human Development, this article outlines the history and future of Cochrane Neonatal, highlighting its role in shaping evidence-based neonatal care through systematic reviews that influence global guidelines.
JOURNAL PUBLICATION | Published in Pediatric Pulmonology, this study assesses availability of therapeutic oxygen, reliability of the electrical supply, and effects of suboptimal oxygen delivery on patient outcomes in rural Kenya.
TOOL | This video provides a brief overview of when oxygen therapy may be necessary in maternity care.
GUIDANCE | This brief provides information on how to manage oxygen therapy in low-resource settings for severe acute respiratory infection and pneumonia in the context of COVID-19.
COURSE / TRAINING VIDEO | This instructional video demonstrates how to use a pulse oximeter in the COVID-19 pandemic.
TOOL | This flowchart lays out use of pulse oximetry in the decision-making process for COVID-19 treatment with oxygen therapy.
JOURNAL PUBLICATION | Published in BMC Pediatrics, this study describes current practice related to the use of HHFNC on pediatric wards and high dependency units, weaning practices, and preferred outcome measures.
GUIDANCE | This guidance highlights proper airway management of patients suspected or confirmed to have COVID-19.
GUIDANCE | This guidance seeks to advise health workers in the pediatric arena during the COVID-19 outbreak in Kenya.
JOURNAL PUBLICATION | Published in the New England Journal of Medicine, this study assessed whether targeting the lower limit of the Pao2 range would improve outcomes in patients with ARDS.
GOVERNMENT POLICY / STRATEGY | The goal of this plan is prevention and control of COVID-19 in Bangladesh to reduce impact on the health, wellbeing, and the economy of the country.
GUIDANCE | This document is intended for clinicians taking care of hospitalized adult and pediatric patients of COVID-19 in India.
JOURNAL PUBLICATION | Published in the American Journal of Tropical Medicine and Hygiene, this retrospective analysis of a prospective cohort study investigates infants participating in pneumonia surveillance in Malawi.
COURSE / TRAINING VIDEO | The World Health Organization developed a series of videos in the 1990s on how to give oxygen to children in low- and middle-income countries.
JOURNAL PUBLICATION | Published in American Journal of Respiratory and Critical Care Medicine, this study assesses hypoxemia in Western Kenya, identifying key factors and suggesting improvements.
JOURNAL PUBLICATION | This study highlighted in the Bulletin of the World Health Organization aims to identify and describe interventions to improve oxygen therapy in hospitals in low-resource settings.
COURSE / TRAINING VIDEO | This course is intended for clinicians who are working in intensive care units in LMICs and managing adult and pediatric patients with severe forms of acute respiratory infection.
REPORT | This brief report presents the causes of pneumonia, the ways to prevent and treat it, and the resources needed to end pneumonia-related deaths.
JOURNAL PUBLICATION | This commentary in Pediatric Pulmonology explores the oxygen gap, using Nigeria as an illustrative case study in improving oxygen access, and concluding with key actions for policy and practice.
JOURNAL PUBLICATION | Published in PLoS Medicine, this study explored when and which pulse oximeters are used for children in Kenyan hospitals, how its use impacts treatment provision, and the barriers to use.
REPOSITORY / TOOLKIT | WHO trauma and emergency surgery kit provides materials and drugs to meet the needs of 50 patients requiring surgical care in emergency situations, assuming two operations per patient.
JOURNAL PUBLICATION | This paper from PLOS Medicine reports the effects of an improved oxygen system on mortality and clinical practices in 12 general, pediatric, and maternity hospitals in southwest Nigeria.
JOURNAL PUBLICATION | The study, published in the Eastern Mediterranean Health Journal, found that targeted interventions improved midwives’ management of postpartum hemorrhage in rural Iran.
JOURNAL PUBLICATION | Published in Seminars in Perinatology, this article emphasizes that retinopathy of prematurity (ROP) is likely to become an increasingly important cause of blindness in children in sub-Saharan Africa.
JOURNAL PUBLICATION | Published in Seminars in Perinatology, the Neonatal Oxygenation Prospective Meta-analysis collaboration reported analysis of five trials of oxygen saturation targeting in very preterm infants.
GOVERNMENT POLICY / STRATEGY | The Federal Government of Nigeria has developed the first-ever national pneumonia control strategy and implementation plan to elevate pneumonia within the integrated newborn and child health agenda.
JOURNAL PUBLICATION | This prospective validation study in BMJ evaluated the effectiveness of intermittent pulse oximetry in guiding oxygen therapy in neonates in a low-resource setting—focusing on three hospitals in southwest Nigeria.
TOOL | This chart booklet provides an overview of the integrated management of childhood illness, specifically as it related to the management of sick and young infants aged up to two months.
JOURNAL PUBLICATION | Published in West African Journal of Medicine, this study found that acute oxygen administration in a Nigerian hospital was often inadequate, with only 40.7% of prescriptions meeting documentation standards.
GOVERNMENT POLICY / STRATEGY | This National Medical Oxygen Scale Up Implementation Plan articulates a holistic approach to improving demand and supply of medical oxygen in Uganda.
JOURNAL PUBLICATION | Published in PLoS One, this study identified barriers to implementing pediatric inpatient care guidelines in nine hospitals across sub-Saharan Africa and South Asia.
JOURNAL PUBLICATION | This study in the journal International Health evaluates the quality of oxygen therapy in 12 secondary-level Nigerian hospitals.
JOURNAL PUBLICATION | Published in PLoS One, this study developed and validated a reliable and valid questionnaire to assess healthcare providers’ knowledge of acute oxygen therapy.
JOURNAL PUBLICATION | Published in the Journal of Global Health Reports, this study describes the use of pulse oximetry during the initial patient assessment among children under five diagnosed with pneumonia in Ethiopia.
JOURNAL PUBLICATION | Published in Tropical Doctor, this letter advocates for universal implementation of newborn pulse oximetry in India to improve early detection of congenital heart disease and reduce neonatal mortality.
JOURNAL PUBLICATION | Published in Archives of Disease in Childhood, this study introduces the Clinical Information Network in Kenya, which applies a Learning Health System model to enhance pediatric care in county hospitals.
JOURNAL PUBLICATION | Published in Critical Care, this research paper argues for the need of establishing a new global focus on essential emergency and critical care (EECC) within the universal health coverage agenda.
JOURNAL PUBLICATION | Published in Médecine et Santé Tropicales, this study on emergency care at the Sylvanus Olympio Teaching Hospital in Lomé found that trauma and appendicitis were common emergencies.
JOURNAL PUBLICATION | Published in Thorax, this descriptive, cross-sectional study describes SpO2 measurements at 15 locations from sea level up to the highest permanent human habitation.
JOURNAL PUBLICATION | Published in BMJ Global Health, this study found that pulse oximetry use in 12 Nigerian hospitals improved from under 5% to over 90% within a year of targeted intervention.
JOURNAL PUBLICATION | Published in BMJ Open, this study assesses the feasibility and performance of early warning scores in a low-middle income country setting, highlighting the potential burden on healthcare staff.
REPORT | To understand the barriers to reducing pneumonia burden, PATH collected and analyzed secondary data and conducted a landscape of key pneumonia stakeholders in the Democratic Republic of the Congo.
REPORT | The information in this report focuses on oxygen access in Kenya and was collected through a combination of desk research and in-country stakeholder interviews and observations.
REPORT | The information in this country report focuses on India and is intended to guide key decision-makers in India as they work to improve access to safe oxygen delivery.
REPORT | The information in this report focuses on oxygen access in Indonesia and was collected through a combination of desk research and in-country stakeholder interviews and observations.
JOURNAL PUBLICATION | Published in Journal of Paediatrics and Child Health, this two-part prospective study examined the hypoxemia prevalence and explored clinical risk factors of neonates in Nairobi, Kenya.
JOURNAL PUBLICATION | Published in BMC Pediatrics, this study audited pediatric deaths at a Malawian hospital, finding that 44% occurred within 24 hrs and were due to malaria, malnutrition, HIV-related illnesses, and sepsis.
GUIDANCE | This manual presents the Advanced Trauma Life Support student course, which does not present new concepts in the field of trauma care; rather, it teaches established treatment methods.
JOURNAL PUBLICATION | This article in the Journal of Perinatology describes a prospective cohort study investigating if the Silverman Andersen respiratory severity score is associated with a need for increased respiratory support.
JOURNAL PUBLICATION | Published in BMJ Open, this cohort study in Brazil showed that infants born at 37-38 weeks’ gestation are at greater risk for adverse outcomes, such as NICU admission and death.
GOVERNMENT POLICY / STRATEGY | The publication of this first comprehensive National Policy on Medical Oxygen marks a significant step in improving access to lifesaving medical oxygen to patients in Nigeria.
JOURNAL PUBLICATION | Published in Implementation Science, the study evaluated a multi-modal intervention using the WHO “Quick Check” triage tool in four Ugandan hospitals.
JOURNAL PUBLICATION | Published in OISR Journal of Nursing and Health Science, interventional study assessed the knowledge level of pediatric nurses in a tertiary care setting, regarding the use of pulse oximeter.
JOURNAL PUBLICATION | Published in the African Journal of Emergency Medicine, this review describes management priorities in emergency care of critically ill children presenting with respiratory problems in resource-limited settings.
JOURNAL PUBLICATION | Published in Journal of Tropical Pediatrics, this study reviews evidence to support oxygen saturation targets for children with emergency signs in developing countries.
JOURNAL PUBLICATION | Published in Trials, this study protocol outlines a trial designed to improve oxygen therapy for children and neonates in Nigerian hospitals through better equipment and healthcare training.
JOURNAL PUBLICATION | Published in Indian Pediatrics, this study compared the performance of respiratory rate and other clinical signs against pulse oximetry for predicting hypoxia in children as per IMNCI classification.
JOURNAL PUBLICATION | Published in Journal of Cardiac Failure, a clinical audit of 200 acute heart failure cases found poor adherence to international guidelines, inadequate documentation, low utilization of diagnostic tests, etc.
JOURNAL PUBLICATION | Published in BMJ Paediatrics Open, this article examines the effect of improved oxygen systems on childhood pneumonia outcomes in district hospitals in Lao PDR.
GUIDANCE | This publication outlines WHO recommendations on adolescent health in one easy-to-access document for WHO staff, policymakers, program managers, and health professionals.
JOURNAL PUBLICATION | Published in Injury, this study explores how continuous quality improvement (CQI) methods improved prehospital trauma care in Rwanda, leading to better patient outcomes.
JOURNAL PUBLICATION | Published in Cost Effectiveness and Resource Allocation, this study evaluates the impact of emerging health innovations on maternal, newborn, and child health to save lives by 2030.
GUIDANCE | ISO 80601-2-61:2017 applies to the basic safety and essential performance of pulse oximeter equipment intended for use on humans.
JOURNAL PUBLICATION | Published in Anaesthesia, this study determined whether the introduction of pulse oximetry with training was feasible and could reduce the incidence of oxygen desaturation during anesthesia in Malawi.
JOURNAL PUBLICATION | In Clinical Infectious Diseases, this article recommends the WHO IMCI guidelines to consider additional referral or daily monitoring criteria for children with chest indrawing pneumonia in low-resource settings.
JOURNAL PUBLICATION | Published in BMJ Open Respiratory Research, this article summarizes the recommendations and good practice points in the British Thoracic Society Guideline for Oxygen Use in Adults.
GOVERNMENT POLICY / STRATEGY | This national strategy aims to reduce mortality and morbidity from hypoxemia in Nigeria by addressing the key gaps in access to medical oxygen.
GUIDANCE | This publication outlines WHO recommendations on child health in one easy-to-access document for WHO staff, policymakers, program managers, and health professionals.
GUIDANCE | This publication outlines WHO recommendations on maternal health in one easy-to-access document for WHO staff, policymakers, program managers, and health professionals.
GUIDANCE | This publication outlines WHO recommendations on newborn health in one easy-to-access document for WHO staff, policymakers, program managers, and health professionals.
JOURNAL PUBLICATION | Published in Anaesthesia, this article highlights the introduction of Lifebox pulse oximeters combined with appropriate training in Malawi.
JOURNAL PUBLICATION | Published in International Journal of Injury Control and Safety Promotion, this study assessed traumatic brain injury care in Tanzania, revealing high mortality among severe patients due to limited interventions.
JOURNAL PUBLICATION | Published in Pan African Medical Journal, this study evaluates the management and outcomes of traumatic brain injury patients at Muhimbili Orthopaedic Institute, highlighting challenges in neurosurgical care in low-income settings.
TOOL | This publication is based on the list of clinical interventions selected from clinical guidelines on prevention, screening, diagnosis, treatment, palliative care, monitoring and end of life care.
JOURNAL PUBLICATION | Published in BMC Health Services Research, this study developed a multi-construct theoretical framework of acceptability of health interventions that can be applied to intervention deliverers and recipients.
GUIDANCE | This manual, and a similar one on preterm and sick newborns, provides guidance for health workers caring for pregnant women and newborns, including when respiratory care is necessary.
JOURNAL PUBLICATION | Published in PLoS One, this study assesses the effectiveness of an intervention package in improving the management and outcomes of neonatal and early childhood sepsis in rural Bangladesh.
JOURNAL PUBLICATION | Published in PLoS One, this study performed an external validation of two prediction tools and compared this to a locally developed tool to identify children admitted with pneumonia in Malawi.
JOURNAL PUBLICATION | Published in the Bulletin of the World Health Organization, this study aims to investigate implementation of outpatient pulse oximetry among children with pneumonia in Malawi.
MULTIMEDIA | This poster presentation from the ASTMH 2016 Annual Meeting summarizes efforts to identify barriers and implement scalable solutions to improve access to oxygen and pulse oximetry.
REPORT | This report highlights current pneumonia and diarrhea related mortality, and illustrates the startling divide between the children being reached and the considerable number of those left behind.
GUIDANCE | This manual focuses on the availability and clinical use of oxygen therapy in children in health facilities by providing the practical aspects for health workers, biomedical engineers, and administrators.
GUIDANCE | WHO’s pediatric emergency triage, assessment and treatment guidelines aim to identify children presenting with airway obstruction and other breathing problems.
GOVERNMENT POLICY / STRATEGY | This roadmap is intended to guide scale up of oxygen and pulse oximeters as well as standardizing the need for comprehensive approach to implementation at all levels throughout Ethiopia.
JOURNAL PUBLICATION | Published in Tropical Medicine and International Health, this study investigates the prevalence of hypoxemia in young children with severe pneumonia in Mozambique and evaluates the effectiveness of clinical prediction models.
JOURNAL PUBLICATION | Published in BMC Pediatrics, this study evaluates the impact of a clinical guidance tool designed to improve outcomes for children hospitalized with severe pneumonia in Zambia.
JOURNAL PUBLICATION | Published in Archives of Disease in Childhood, this review indicates that pulse oximetry can improve health outcomes for children by reducing mortality and length of stay.
JOURNAL PUBLICATION | Published in Anesthesia & Analgesia, this study evaluated the accuracy of 6 low-cost finger pulse oximeters during stable arterial oxygen saturations (SaO2) between 70% and 100% in 22 healthy subjects.
JOURNAL PUBLICATION | Published in Pneumonia (Nathan Qld), the aim of this study was to evaluate the need for supplementary oxygen against oxygen delivery capacity at a large teaching hospital in Malawi.
JOURNAL PUBLICATION | This systematic review in the World Journal of Surgery examines the results of anesthesia care capacity assessments in LMICs to identify patterns of deficits and useful targets for intervention.
JOURNAL PUBLICATION | Published in African Journal of Medicine and Medical Science, this study assesses structural, technical, and clinical barriers to the provision of safe and effective oxygen therapy in Nigeria.
COURSE / TRAINING VIDEO | This video informs viewers on how to identify clinical signs and symptoms of respiratory distress in a pediatric patient.
JOURNAL PUBLICATION | Published in The Lancet Global Health, this study investigates the mortality and risk factors in Malawian children hospitalized with pneumonia, highlighting delayed care, malnutrition, etc.
JOURNAL PUBLICATION | This study in Nature uses a deterministic compartmental model to assess the impact of introducing pulse oximetry as a prognostic tool to distinguish severe from non-severe pneumonia in children.
JOURNAL PUBLICATION | This systematic review and meta-analysis in PLOS One examines observational studies to evaluate the association between hypoxemia and mortality from acute lower respiratory infections in children in LMICs.
JOURNAL PUBLICATION | Published in The Lancet, this study assessed whether the 90% or higher target for oxygen supplementation was equivalent to a normoxic 94% or higher target for infants with viral bronchiolitis.
JOURNAL PUBLICATION | Published in BMC Pediatrics, this study characterizes the operational feasibility and parent/guardian acceptability of incorporating pulse oximetry into the routine clinical assessment of young infants in Pakistan.
JOURNAL PUBLICATION | Published in South African Journal of Child Health, this study assesses the impact of hypoxemia on severity and outcome of pediatric pneumonia, showing its predictive value for hospitalization and death.
JOURNAL PUBLICATION | Published in Paediatric International Child Health, this study examines neonatal admissions at a hospital in The Gambia, identifying key mortality risk factors and recommending improved IPC strategies.
COURSE / TRAINING VIDEO | Chest indrawing is a sign of severe pneumonia. It means the child need to be treated immediately. This video highlights the key signs of chest indrawing in children.
COURSE / TRAINING VIDEO | Children with pneumonia breathe faster than normal. This video highlights the steps to properly count breaths for pneumonia diagnosis and when to seek medical attention.
JOURNAL PUBLICATION | Published in American Journal of Respiratory and Critical Care Medicine, this study examined the potential morbidity attributable to quality of care received during neonatal transportation due to hypoxemia in Nigeria.
JOURNAL PUBLICATION | Published in Archivos de Bronconeumología, this study found that while empiric antibiotic therapy for hospitalized CAP patients in Venezuela was timely, adherence to other national guidelines was low.
JOURNAL PUBLICATION | Published in Cad Saude Publica, this study highlighted poor compliance with optimal clinical practices in the care of healthy full-term newborns in Brazil, with widespread overuse of certain interventions.
JOURNAL PUBLICATION | Published in JAMA, this study examined if Canadian infants with bronchiolitis who displayed artificially elevated oximetry measurements experience lower hospitalization rates compared with control infants.
JOURNAL PUBLICATION | Published in PLoS One, this study evaluated the pneumonia case fatality rate following the implementation of a Child Lung Health Programme in Malawi to improve delivery of pneumonia case management.
GUIDANCE | The purpose of this document is to provide a summary of WHO-approved pneumonia control recommendations and to assist national child health programs in revising their guidelines to conform to them.
TOOL | This chart booklet, which provides an overview of the integrated management of childhood illness, belongs to a set of distance learning courses from the World Health Organization (WHO).
JOURNAL PUBLICATION | This study in Tropical Medicine & International Health surveyed Cambodian clinicians to better understand the availability of oxygen and pulse oximetry, barriers to use, and clinician perceptions and practices.
JOURNAL PUBLICATION | Published in Cochrane Database of Systematic Reviews, this review examined perioperative monitoring with pulse oximetry to identify adverse outcomes that might be prevented or improved by its use.
JOURNAL PUBLICATION | A randomized controlled trial recently demonstrated that CPAP effectively decreases respiratory rate in children presenting to Ghanaian district hospitals with respiratory distress.
JOURNAL PUBLICATION | Published in Pediatrics, this study found that pulse oximetry overestimates arterial oxygen saturation (SaO₂) in children, particularly in the hypoxemic range (76%-90%).
JOURNAL PUBLICATION | Published in Respiratory Care, this paper emphasizes evidence for use with other health conditions for which oxygen is administered relies on anecdotal experiences, case reports, or small, underpowered studies.
JOURNAL PUBLICATION | This study investigated prevalence and predictors of hypoxemia in ALRI and non-ALRI according to age and primary diagnoses in emergently ill children in south western Nigeria.
JOURNAL PUBLICATION | This study describes the profile of care provided by a Mobile Emergency Care Service in Brazil, aiming to contribute to the planning and organization of mobile emergency services.
JOURNAL PUBLICATION | This article in the Annals of Tropical Pediatrics reviews pulse oximetry, its technical basis, and its application to the medical management of childhood illness to reduce mortality in developing countries.
JOURNAL PUBLICATION | Published in ISRN Pediatrics, this study identifies key predictors of hypoxemia in rural Gambia, particularly grunting and cyanosis, and children with these signs should be given oxygen therapy.
GOVERNMENT POLICY / STRATEGY | The integrated Global Action Plan for the Prevention and Control of Pneumonia and Diarrhea (GAPPD) proposes a cohesive approach to ending preventable pneumonia and diarrhea deaths.
JOURNAL PUBLICATION | Published in Pediatric Emergency Care, this retrospective, comparative study applied quality indicators in respiratory disease triage to all patients attending an emergency department in Paraguay.
JOURNAL PUBLICATION | Published in JAMA Pediatrics, this study demonstrates that implementing an OU-HOT protocol for bronchiolitis in children reduces hospital stays and healthcare costs, while maintaining patient safety.
JOURNAL PUBLICATION | The aim of this study was to evaluate the clinical practices in delivery room in Brazil and identify if there are inequalities in healthy term newborn care immediately after birth.
JOURNAL PUBLICATION | Published in Annals of Surgery, this article explores the impact of implementing the WHO Surgical Safety Checklist and pulse oximetry in a resource-limited hospital.
JOURNAL PUBLICATION | This article describes the process for developing the ACCF/AHA practice guidelines for cardiovascular care to assist healthcare providers in clinical decision making.
GUIDANCE | This pocket book for hospital care for children is one of a series of documents and tools that support the Integrated Management of Childhood Illness (IMCI).
JOURNAL PUBLICATION | Published in PLoS One, this study explored the predictors of hypoxemia in under-five children who were hospitalized for the management of pneumonia and severe acute malnutrition in Bangladesh.
JOURNAL PUBLICATION | Published in Ontario Health Technology Assessment Series, this study found that COPD smoking cessation programs were cost-effective, while multidisciplinary care and pulmonary rehabilitation were also beneficial but costly.
JOURNAL PUBLICATION | Published in PLoS Medicine, this article proposes maternal and newborn signal functions, focusing on delivery and postnatal care, which could be used to characterize both routine and emergency care.
JOURNAL PUBLICATION | Published in Trauma Monthly, this study assessed the adherence to the WHO surgical safety checklist at hospitals in Tehran and found that overall observance was moderate.
JOURNAL PUBLICATION | This study aimed to review the quality of initial trauma resuscitation in a regional hospital in South Africa and determine quality indicators to measure improvements after potential interventions.
JOURNAL PUBLICATION | Published in Respiratory Medicine, this study assesses longitudinal incidence rates for community-acquired pneumonia in chronic obstructive pulmonary disease (COPD) patients or risk factors for pneumonia onset.
JOURNAL PUBLICATION | Published in Journal of the Joint Commission on Quality and Patient Safety, this study analyzes the impact of the WHO Surgical Safety Checklist on surgical care in Liberia.
JOURNAL PUBLICATION | Published in Respiration, this study aimed to test the hypothesis that in healthy volunteers, normal arterial hemoglobin oxygen saturation at moderate altitude is lower than that at almost sea level.
JOURNAL PUBLICATION | This study in Journal of Tropical Pediatrics surveyed clinicians in resource-limited countries to better understand the availability of oxygen and pulse oximetry, barriers to use, and clinician perceptions and practices.
JOURNAL PUBLICATION | As part of a larger study, this study—published in BMC Health Services Research—explored how well interventions supported better health services for neonatal illnesses and severe malnutrition in Kenya.
JOURNAL PUBLICATION | Published in Pediatrics, this review describes the physiologic principles and limitations of pulse oximetry, discusses normal values, and highlights its importance in common pediatric diseases.
GUIDANCE | This manual describes how oximeters work and how to use them so that all anesthesia providers who are not experienced in using pulse oximetry.
COURSE / TRAINING VIDEO | This video highlights the considerations of administering oxygen therapy in acute illness.
COURSE / TRAINING VIDEO | This video highlights the considerations of administering oxygen therapy in acute illness. This first session covers how to quickly assess if supplemental oxygen is needed.
JOURNAL PUBLICATION | Published in American Journal of Respiratory and Critical Care Medicine, this prospective cross-sectional study examined hypoxia in children and the decision to give oxygen in a Nigerian hospital.
JOURNAL PUBLICATION | Published in International Journal of Tuberculosis and Lung Disease, this meta-analysis found that clinical symptoms alone are unreliable for predicting hypoxemia in children with acute respiratory infections.
JOURNAL PUBLICATION | Published in Archives of Disease in Childhood-Fetal and Neonatal Edition, this study examined the number of premature newborns assigned to NICU nurses and achievement of oxygen saturation goals.
GUIDANCE | This manual is written for clinicians working at the district hospital (first-level referral care) who diagnose and manage sick adolescents and adults in resource-constrained settings.
JOURNAL PUBLICATION | Published in the African Journal of Respiratory Medicine, this study was carried out to determine the level of knowledge and competencies relating to the use of pulse oximetry for children.
JOURNAL PUBLICATION | This study in the Papua New Guinea Medical Journal reviews the methods for providing oxygen in Papua New Guinea.
JOURNAL PUBLICATION | Published in the International Journal of Emergency Medicine, this cross-sectional analysis of the prevalence of hypoxemia was conducted in Kapiri Mposhi, Zambia, at the 60-bed district hospital.
GUIDANCE | These guidelines are part of a comprehensive set of normative documents for the prevention and treatment of common conditions affecting HIV-infected and -exposed infants and children.
JOURNAL PUBLICATION | Published in the Journal of Perinatology, this qualitative study explored nurses’ perceptions of what makes them compliant with alarm limits for pulse oximetry in preterm infants in Germany.
JOURNAL PUBLICATION | Published in Paediatric Anaesthesia, this retrospective study examined the practice of pediatric anesthesia at two hospitals in Benin.
JOURNAL PUBLICATION | Published in Support Care Cancer, this study reported the prevalence and experience of dyspnea, pattern of oxygen use, and patients’ perceived benefits/burdens of oxygen therapy in home palliative care.
JOURNAL PUBLICATION | Published in Anaesthesia, this article discusses the international anaesthesia quality improvement project focused on expanding the availability and use of pulse oximetry in hospitals across low-resource settings.
JOURNAL PUBLICATION | Published in Journal of Clinical Engineering, this survey evaluates 11 oxygen concentrator models for use in tropical countries, identifying the most effective models based on performance, cost, etc.
JOURNAL PUBLICATION | The study, published in the Bulletin of the World Health Organization, found that 6.4% of neonates and young children admitted to a Kenyan hospital had hypoxemia.
JOURNAL PUBLICATION | In this review of studies of acute lower respiratory tract infection in The Lancet Infectious Diseases, the median prevalence of pneumonia hypoxemia requiring hospitalization was 13%, but prevalence varied widely.
JOURNAL PUBLICATION | Published in The New England Journal of Medicine, this study found that implementing a 19-item Surgical Safety Checklist across eight hospitals worldwide reduced surgical mortality.
JOURNAL PUBLICATION | This study in The Lancet examines the effect of an improved oxygen system on death rate in children with pneumonia in Papua New Guinea.
JOURNAL PUBLICATION | This article in The Lancet reports that the implementation of oxygen therapy and monitoring systems can be a feasible cost-effective step forward, and can save lives.
JOURNAL PUBLICATION | Published in Annals of Tropical Paediatrics, this article examines the implementation of an oxygen programme in hospitals in Papua New Guinea to improve child survival rates.
JOURNAL PUBLICATION | This study in Anesthesia and Analgesia looks at the relationship between skin pigment and oximeter accuracy in 36 subjects (19 males, 17 females) of a range of skin tones.
JOURNAL PUBLICATION | Published in Medicina (Buenos Aires), this study assessed the adherence to national guidelines for community-acquired pneumonia care in Argentina.
JOURNAL PUBLICATION | Published in Journal of Tropical Pediatrics, this article identifies clinical signs that predict hypoxemia in children with pneumonia, helping guide treatment decisions in low-resource settings.
JOURNAL PUBLICATION | This article in the Journal of Perinatology goes over retinopathy of prematurity, particularly the role of oxygen in the disease, and the recent advances in its diagnosis and treatment.
JOURNAL PUBLICATION | Published in Tropical Medicine and International Health, this study investigated the prevalence and predictive value of hypoxia in ALRI and other acute infectious diseases in children in The Gambia.
JOURNAL PUBLICATION | The study in the journal Anesthesiology showed that the three tested pulse oximeters overestimated arterial oxygen saturation during hypoxia in dark-skinned individuals.
JOURNAL PUBLICATION | Published in The Lancet, this study assessed pediatric care at district hospitals in Kenya, highlighting variability in care quality and resource availability.
JOURNAL PUBLICATION | Published in Resuscitation, the aim of this study was to determine the predictive value of selected abnormal clinical observations in a ward population for subsequent in-hospital mortality in Australia.
JOURNAL PUBLICATION | Published in The Lancet, the study evaluated pediatric inpatient care in 13 Kenyan district hospitals, finding significant gaps in care practices and data quality.
JOURNAL PUBLICATION | Published in SciELO Brasil, the study found that a clinical protocol for acute asthma in the ER improved diagnostic assessments and adherence to recommended treatments.
GUIDANCE | This guide is designed to assist countries with limited resources in their efforts to reduce neonatal mortality and to ensure care for newborn babies facing complications of pregnancy and childbirth.
JOURNAL PUBLICATION | Published in American Journal of Emergency Medicine, this study evaluated the prediction of life-threatening disease or death among transported patients with acute chest pain or other symptoms in Sweden.
JOURNAL PUBLICATION | This article in the Archives of Disease in Childhood. Fetal and Neonatal Edition lays out the main methods of oxygen administration to infants.
JOURNAL PUBLICATION | Published in Archives of Disease in Childhood, this study explores hypoxemia in children with both ALRI and non-ALRI illnesses in Papua New Guinea.
JOURNAL PUBLICATION | Published in the International Journal of Tuberculosis and Lung Disease, this study reviewed the prevalence and risk factors of hypoxemia in children under 5 with acute lower respiratory infections.
JOURNAL PUBLICATION | Published in International Journal of Tuberculosis and Lung Disease, this study explores hypoxemia severity in children with pneumonia in Papua New Guinea.
JOURNAL PUBLICATION | Published in The Lancet, this qualitative study assessed initial triage, emergency and inpatient care, staff knowledge and practices, and hospital support services in seven less-developed countries.
JOURNAL PUBLICATION | Published in BMJ, this prospective cohort study found that simple physical signs could predict hypoxemia in children with acute lower respiratory tract infections in The Gambia.
JOURNAL PUBLICATION | Published in European Respiratory Journal, this trial shows that while liquid oxygen therapy is more costly than concentrator treatment, it provides substantial improvements in quality of life for chronic patients.
JOURNAL PUBLICATION | Published in Annals of Emergency Medicine, this study showed that clinical evaluation alone was insufficient to detect low oxygen saturation in pediatric patients.
JOURNAL PUBLICATION | Published in the European Respiratory Journal, this study analyzes home treatment practices for chronic respiratory insufficiency across 13 European countries, identifying key differences in policy, equipment use, and patient supervision.
JOURNAL PUBLICATION | Published in BMJ, this study examines the prevalence and clinical predictors of hypoxemia in young children with acute respiratory infections in Kenya.
JOURNAL PUBLICATION | Published in Chest, this article makes the case for oxygen saturation (SpO2) measured by pulse oximetry as an essential fifth vital sign in all sick children.
JOURNAL PUBLICATION | Published in Tropical Doctor, this study looks at the use of oxygen concentrators in a remote hospital in Zaire, now the Democratic Republic of the Congo.
COURSE / TRAINING VIDEO | This course covers crucial factors that determine oxygenation of blood in the lungs and oxygen transport and delivery to peripheral tissues.
GUIDANCE | These expert-vetted articles and infographics provide guidance on the clinical management of COVID-19 patients, ICU administration, procedures, supply chain issues, and treatment.
GUIDANCE | This guidance covers various clinical aspects of oxygen delivery, including patient assessment, indications for oxygen delivery, weaning, high- vs low-flow, etc.
GUIDANCE | The EECC Network is an informal and independent global community-of-practice of clinicians, researchers, policymakers, and others interested in Essential Emergency and Critical Care.
REPOSITORY / TOOLKIT | The mission of this learning platform is to improve equity in peri-operative healthcare access through medical education, engaging discussions, remote mentorship, and building professional networks.
REPOSITORY / TOOLKIT | This toolkit brings together knowledge, experiences, resources, and learnings for implementing small and sick newborn care services.
COURSE / TRAINING VIDEO | This course covers the history, development, and clinical application of pulse oximetry; how a pulse oximeter works; why it is critical to monitor oxygenation saturation; and caveats of pulse oximetry.
COURSE / TRAINING VIDEO | This course provides healthcare providers with an understanding of the role of oxygen therapy in critical care.
COURSE / TRAINING VIDEO | This course covers the indications for noninvasive ventilation, initiation and optimization, how to monitor patients, and how to wean them from it.
REPOSITORY / TOOLKIT | This site (currently in beta) aims to help healthcare workers in resource-variable settings find open-access, high-quality critical care learning resources–starting with respiratory care.
TOOL | This list provides research study protocols to maximize accuracy, equity, and comparability of data collected by oximeter performance studies worldwide.
REPOSITORY / TOOLKIT | The OCC Encyclopedia contains articles written by OCC editors and partners. Soon users will be able to find answers to everything to know about oxygen in this open-access, peer-reviewed encyclopedia.
TOOL | This webpage provides up-to-date, expert answers to frequently asked questions (FAQ) about oxygen supply systems, respiratory care and pulse oximetry written by OCC and collaborators.
GUIDANCE | This resource guides through procedures unique to the adult progressive and critical care environment, including those performed by advanced practice nurses, in a step-by-step format.
TOOL | This frequently asked questions provides up-to-date, expert answers about oxygen supply systems, respiratory care, and pulse oximetry written by Open Critical Care and collaborators.
COURSE / TRAINING VIDEO | This short, intermediate-level course is for frontline health workers caring for patients with suspected or confirmed seasonal influenza infection.
REPOSITORY / TOOLKIT | This website provides a one-stop shop for all oxygen resources compiled by WHO, including requirements of medicinal oxygen, components of an oxygen system, guidelines, factsheets, and more.
REPOSITORY / TOOLKIT | AFEM’s resources are Africa-specific for clinical, nursing, and pre-hospital emergency care.
COURSE / TRAINING VIDEO | This course was developed due to the enormous emphasis placed on need for safe provision of oxygen to patients with COVID-19, but can be used for conditions beyond COVID-19.
REPOSITORY / TOOLKIT | This toolkit provides answers to many questions related to COVID-19. The answers were curated from evidence-based literature and peer-reviewed resources.
GUIDANCE | This webpage highlights World Health Organization guidance and resources on the use of medical oxygen.
REPOSITORY / TOOLKIT | Medevis is an open access WHO electronic database on appropriate medical devices according to the levels of care, setting and intended health intervention.
TOOL | This resource provides a list of various makes and models of existing pulse oximeters.
TOOL | This website provides the oxygen technology from Fritz Stephan GmbH – tailor-made ventilation solutions for premature infants, children, and adults.
PRESENTATION / WEBINAR | The Oxygen Talk is where the Oxygen Alliance invites experts to come and speak about an oxygen-related topic.
ARTICLE | UNICEF’s Oxygen Therapy Project, jointly with the World Health Organization, aims to provide governments with practical tools for building oxygen systems in their countries.
TOOL | This assessment should be completed with input from healthcare providers with current, firsthand knowledge of the facility’s intensive care and oxygen infrastructure.
REPOSITORY / TOOLKIT | The WHO Access to Oxygen Initiative provides technical and operational support to Member States on solutions to enable a resilient oxygen ecosystem.
COURSE / TRAINING VIDEO | As part of the COVID-19 response, WHO developed a series of training videos for medical equipment related to oxygen therapy.
GOVERNMENT POLICY / STRATEGY | The Kenya Medical Oxygen Roadmap is set to ensure equitable access to high-quality, sustainable, and affordable medical oxygen for all Kenyans by 2030.
TOOL | This series highlights country examples where tools from the Oxygen Delivery Toolkit helped stakeholders to plan, manage, and communicate the value of scaling up oxygen.
JOURNAL PUBLICATION | Published in The Lancet, this prospective study examined all inpatients >18 years to assess the co-primary outcomes of critical illness and 7-day mortality in acute hospitals across Africa.
PRESENTATION / WEBINAR | WHO hosted a virtual workshop series to introduce practical and applicable knowledge for Member States and partners to expand on or develop costed national oxygen scale-up plans.
JOURNAL PUBLICATION | Published in Frontiers in Public Health, this study evaluates the implementation of a short-term respiratory care training to rapidly build health worker capacity during the COVID-19 response in Liberia.
JOURNAL PUBLICATION | Published in The Lancet Global Health, this paper emphasizes engaging local champions (like nurses), providing them with knowledge and resources, and then empowering them to act to ensure sustainable change.
INFORMATION BRIEF | Published in The Lancet Global Health, these testimonials share the experiences of patients and their caregivers and shaped the recommendations of The Lancet Global Health Commission on Medical Oxygen Security.
JOURNAL PUBLICATION | Published in Annals of the American Thoracic Society, this study determines the prevalence, clinical care, and outcomes for hospitalized hypoxemic adults in Kenya, Malawi, and Rwanda.
JOURNAL PUBLICATION | Published in Pediatrics and Child Health, this review article focuses on the difficulties of titrating oxygen therapy in preterm infants and provides recommendations for best practice based on up-to-date evidence.
JOURNAL PUBLICATION | Published in Heart, this study aimed to compare standard manual oxygen administration with automated oxygen administration (AOA) using the O2matic device.
COURSE / TRAINING VIDEO | Developed by WHO, this training provides an introduction to oxygen systems, including the oxygen ecosystem, quality assurance and quality control, improving the safety of medical oxygen systems, etc.
GUIDANCE | This guideline serves as a useful and practical guide in the selection of optimal medical oxygen source modalities, usage, administration, and conservation of medical oxygen as well as safety aspects.
REPORT | This report analyzes data collected via facility assessments to provide a snapshot of the medical oxygen ecosystem from 113 health facilities in seven counties across Kenya.
REPORT | This report analyzes and presents data collected during facility assessments in 14 provinces across Senegal, by service ward, to provide a snapshot of the country’s oxygen ecosystem.
REPORT | The purpose of this assessment is quantifying the Tanzania’s capacity to produce, distribute, and utilize medical oxygen. Results demonstrate that oxygen production covers only 20% of estimated oxygen need.
REPORT | This report analyzes data collected through facility assessments from 340 health facilities in 26 provinces across DRC to provide a snapshot of their medical oxygen ecosystem.
JOURNAL PUBLICATION | Published in medRxiv, this study assesses household out-of-pocket costs for children under-5 receiving IMCI consultations in four African countries.
JOURNAL PUBLICATION | Published in medRxiv, this study describes AIRE project intervention sites in Burkina Faso, Guinea, Mali, and Niger and measures their capacity to offer IMCI-care prior to project implementation.
JOURNAL PUBLICATION | Published in Annals of the American Thoracic Society, this study aimed to quantify the association between potential risk factors and chronic hypoxemia among adults hospitalized in Kenya.
JOURNAL PUBLICATION | Published in Patient Safety, this study examines the contributing factors and context of oxygen disruption–related patient safety event reports in the inpatient setting and provides solutions.
JOURNAL PUBLICATION | Published PLoS Global Public Health, this study measures the effectiveness of deploying trained and equipped CHWs in reducing COVID-19 infections and deaths in two counties in rural Western Kenya.
JOURNAL PUBLICATION | Published in the Journal of Global Health, this sub-analysis of the COVID-19 Critical Care Consortium database assesses the oxygen consumption requirements of COVID-19 patients admitted to intensive care units.
JOURNAL PUBLICATION | Published in BMJ Open, this exploratory qualitative study identifies delays in delivery of care to critically ill patients and possible ways to address these delays in four public Kenyan hospitals.
JOURNAL PUBLICATION | Published in the British Journal of Surgery, this study examines the effectiveness of a standardized trauma intake form for improving key performance indicators in initial trauma care in Ghana.
REPOSITORY / TOOLKIT | This resource library, managed by Assist International, provides various tools and resources on COVID-19 treatment and care, including surgical care, oxygen therapy, infection control, and resource planning.
GOVERNMENT POLICY / STRATEGY | Their second iteration, this oxygen roadmap provides a comprehensive approach to overcome prevailing bottlenecks and improve access to medical oxygen, diagnostics, and hypoxemia management.
JOURNAL PUBLICATION | Published in BMJ Open, this study aims to describe the requirements and use of oxygen at the facility and patient level of approximately 4,500 patients with COVID-19 in 30 countries.
GOVERNMENT POLICY / STRATEGY | Under the four interdependent strategic objectives, this strategy provides policy and implementation framework for scaling up medical oxygen within the system in Lesotho.
JOURNAL PUBLICATION | Published in Frontiers in Public Health, this study attempted to investigate the journey of patients with COPD in the healthcare system using nationally representative data in Iran.
GOVERNMENT POLICY / STRATEGY | The Zambian National Medical Oxygen Strategic Plan 2022–2026 provides strategic direction for ensuring the supply of safe medical oxygen needed to manage clients with respiratory conditions, including COVID-19.
JOURNAL PUBLICATION | Published in BMC Infectious Diseases, this study compares four epidemic waves of COVID-19 in Malawi and explores the relationship between viral lineage and outcomes for adult COVID-19 patients.
JOURNAL PUBLICATION | Published in the Journal of Global Health, this review aimed to identify the most important risk factors for mortality among children aged under ten years with pneumonia.
GOVERNMENT POLICY / STRATEGY | This policy establishes the framework and lay the foundation for a national strategy for scaling-up production, availability, access, and use of medical oxygen across Ghana.
GUIDANCE | The WHO Therapeutics and COVID-19: living guideline contains the most up-to-date recommendations for the use of therapeutics in the treatment of COVID-19.
ARTICLE | This webpage provides answers to key questions about stillbirths.
GOVERNMENT POLICY / STRATEGY | The overarching objective of this operational plan is to improve access to medical oxygen for all people in Eswatini and ensure effective use to save lives by the year 2025.
REPORT | This NEST360 report outlines a compendium of newborn healthcare technologies, both commercially available and in development, suitable for use in resource-limited settings.
JOURNAL PUBLICATION | Published in NeuroQuantology, the study examines how Kerala’s eHealth project, incorporating telemedicine and digital health tools, supported healthcare during the pandemic.
REPORT | This report provides survey results related to use of Zambia’s oxygen data dashboard, which demonstrates many were aware of the dashboard, but most did not use it regularly.
JOURNAL PUBLICATION | Published in Journal of Pharmaceutical Sciences, this review evaluates the updated European Medical Device Regulations and their global impact, emphasizing stricter compliance requirements post-COVID-19.
GUIDANCE | The WHO developed a technical series to expand the expertise in medical devices to support member states to ensure improved access, quality and use of medical products and technologies.
INFORMATION BRIEF | This success story highlights the importance of upskilling and capacity strengthening of internal technicians and healthcare service providers within a hospital in India
INFORMATION BRIEF | This factsheet offers an overview of the Strengthening Oxygen Utilization and Respiratory Care Ecosystems (SOURCE) project to support countries to equitably improve oxygen access.
TOOL | The NEST360 qualified technologies are a list of newborn care technologies best suited for use in low-resource setting hospitals, including being effective, affordable, rugged, and simple to use.
GOVERNMENT POLICY / STRATEGY | This plan aims to ensure availability, accessibility, and affordability of quality medical oxygen therapy to meet universal health coverage in the country.
JOURNAL PUBLICATION | Published in BMC Health Services Research, this study aimed to assess the knowledge, attitude, and practice of health professionals towards oxygen therapy.
JOURNAL PUBLICATION | Published in the Rawal Medical Journal, this study evaluates the quality of care of patients with acute exacerbation of COPD and the change in practice after educational program and recommendations.
JOURNAL PUBLICATION | Published in Respirology, this update to the Thoracic Society of Australia and New Zealand (TSANZ) guidance on acute oxygen therapy is a brief and practical resource for health workers.
TOOL | This questionnaire supports the creation of a data set to help evaluate national capacity for anesthesia care and to provide guidance for improving or maintaining safe anesthesia standards.
REPORT | This report summarizes observations from the collected data of a biomedical equipment survey and is intended to help global and national stakeholders understand COVID-19 treatment capacity in DRC.
PRESENTATION / WEBINAR | This webinar focuses on key elements to consider in the clinical management of mild, moderate, or severe COVID-19 in children and young persons.
PRESENTATION / WEBINAR | This presentation outlines the activities of The Luke Commission in improving comprehensive health services in Eswatini, including efforts to scale up COVID-19 vaccination and strengthening oxygen delivery.
JOURNAL PUBLICATION | Published in The Lancet Global Health, this study presents an estimated number of children who are admitted to hospital due to pneumonia with hypoxemia annually.
GUIDANCE | This website provides useful information to clinicians about helmet use for noninvasive ventilation in patients who have respiratory distress as a complication of COVID-19.
JOURNAL PUBLICATION | Published in Health and Technology, this article aims to create awareness about commonly used medical devices during the COVID-19 pandemic and to survey trust in home usable devices in India.
JOURNAL PUBLICATION | Published in BMJ Open, the aim of this study was to explore how the COVID-19 pandemic changed the working conditions of physicians in Swedish primary healthcare.
TOOL | This poster is intended for healthcare workers, biomedical engineers, and staff in charge of caring, cleaning, decontaminating, and sterilizing respiratory equipment like pulse oximeters and patient monitors.
ARTICLE | Published in JAMA Network, this editorial posits how best to prepare hospitals’ medical oxygen delivery ecosystems for health emergencies.
JOURNAL PUBLICATION | This study (published in American Journal of Respiratory and Critical Care Medicine) sought to identify healthcare facilities that were adequately resourced to manage severe pediatric pneumonia.
TOOL | This collection of posters are intended for healthcare workers, biomedical engineers, and staff in charge of caring, cleaning, decontaminating, and sterilizing respiratory medical equipment in health facilities.
TOOL | This collection of posters are intended for healthcare workers, biomedical engineers, and staff in charge of caring, cleaning, decontaminating, and sterilizing respiratory medical equipment in health facilities.
TOOL | This collection of posters are intended for healthcare workers, biomedical engineers, and staff in charge of caring, cleaning, decontaminating, and sterilizing respiratory medical equipment in health facilities.
JOURNAL PUBLICATION | Published in BMJ Global Health, this paper reviews evidence on the effectiveness of strengthening oxygen systems on mortality for children with pneumonia to populate estimates in the Lives Saved Tool.
JOURNAL PUBLICATION | Published in the Journal of Perinatology, this study provides more comprehensive data on the management of oxygen supplementation in neonates in sub-Saharan Africa.
JOURNAL PUBLICATION | Published in BMJ Global Health, this article systematically reviewed studies of any design comparing one group where pulse oximetry was used and at least one group where it was not.
JOURNAL PUBLICATION | The World Federation of Societies of Anesthesiologists (WFSA) has developed the “WFSA—Minimum Capnometer Specifications 2021”, which are published in Anesthesia & Analgesia.
GOVERNMENT POLICY / STRATEGY | This strategic plan for oxygen therapy aims to achieve 100% oxygen coverage at each level of the health system in Madagascar, through autonomy of oxygen production at the regional level.
JOURNAL PUBLICATION | Published in BMJ, this study characterizes the adoption and explores specific clinical and patient factors that might influence pulse oximetry and oxygen use in LMICs over time.
ARTICLE | Published on Gas World, this article explores oxygen supply chain shortages that ultimately failed to prevent the loss of many thousands of lives.
ARTICLE | Published on Gas World, this articles provides an overview of lessons learned from past epidemics and the interplay between political playbooks and pandemic preparedness.
JOURNAL PUBLICATION | Published in PLOS One, this study suggests a quality-of-care gap that may negatively affect COVID-19 outcomes and recommends a focus on quality of essential care in the COVID-19 response.
JOURNAL PUBLICATION | Published in BMC Health Services Research, this article describes the approach to co-design a newborn monitoring chart in Kenya using human-centered design, as a means to reduce neonatal mortality.
REPORT | This report highlights an assessment of biomedical equipment in Pakistan, especially focusing on oxygen supply systems.
JOURNAL PUBLICATION | This narrative review published in Respiratory Care systematically analyzes whether COVID-19–associated respiratory failure is essentially ARDS, with perhaps a somewhat different course of presentation.
TOOL | This clinical job aid from NEST360 provides an overview of an Acare suction pump, including assessment and preparation as well as repair and maintenance of the device.
TOOL | This clinical job aid from NEST360 provides an overview of an AirSep oxygen concentrator, including assessment and preparation as well as repair and maintenance of the device.
TOOL | This clinical job aid from NEST360 provides an overview of an Aspeed suction pump, including assessment and preparation as well as repair and maintenance of the device.
TOOL | This clinical job aid from NEST360 provides an overview of a bubble CPAP device.
TOOL | This clinical job aid from NEST360 provides an overview of a Canta oxygen concentrator, including assessment and preparation as well as repair and maintenance of the device.
TOOL | This clinical job aid from NEST360 provides an overview of a flow splitter, including assessment and preparation as well as repair and maintenance of the device.
COURSE / TRAINING VIDEO | These NEST360 training videos demonstrate model-specific equipment setup, use, and maintenance and are used as training aids in clinical and technical training.
REPORT | This report outlines the results of a rapid desk research exercise on maternal, neonatal, and child health (MNCH) medical devices and the challenges/barriers they face.
JOURNAL PUBLICATION | Published in Frontiers in Public Health, this study examined whether variation in national oxygen guidelines had any association with COVID-19 mortality rates looking at the 29 worst-affected countries.
GUIDANCE | WHO convened a consultation, held over four meetings, with groups that have proven experience implementing oxygen scale up activities to accelerate oxygen access at the country level.
JOURNAL PUBLICATION | This article in American Society of Tropical Medicine and Hygiene argues the imperative to consider scalable, sustainable approaches to providing oxygen to those in greatest need at a policy level.
REPORT | This report summarizes observations from the collected data of a biomedical equipment survey and is intended to help global and national stakeholders understand COVID-19 treatment capacity in Zambia.
PRESENTATION / WEBINAR | This WHO webinar highlights the challenges and solutions in the systems response for oxygen in COVID-19 clinical settings.
TOOL | To assist in preparing staff and teams, Laerdal Medical and partners have created a set of free scenarios to better address COVID-19.
JOURNAL PUBLICATION | Published in BMJ Global Health, this study analyzes neonatal mortality in Kenyan hospitals, identifying major risk factors and calling for improved prenatal and neonatal care to reduce mortality.
JOURNAL PUBLICATION | The African COVID-19 Critical Care Outcomes Study aimed to determine which resources, comorbidities, and critical care interventions are associated with mortality in African critically ill COVID-19 patients.
TOOL | These respiratory care order set templates cover the key principles for respiratory care for both adult and pediatric patients.
TOOL | This pocket guide contains quick reference for airway management, common induction and sedation agents and more.
TOOL | This collection of tools is a resource to support meaningful assessments and better target effective interventions for those who are building the oxygen ecosystem.
REPORT | This report summarizes observations from the collected data of a biomedical equipment survey and is intended to help global and national stakeholders understand COVID-19 treatment capacity in Kinshasa, DRC.
REPORT | This report summarizes observations from the collected data of a biomedical equipment survey and is intended to help global and national stakeholders understand COVID-19 treatment capacity in Senegal.
PRESENTATION / WEBINAR | This video by the All India Institute Of Medical Sciences (AIIMS), New Delhi discusses the update on current medical management of COVID-19, including for oxygen therapy.
TOOL | This tool from NEST360 provides a technical scenario for a pulse oximeter.
PRESENTATION / WEBINAR | This webinar series highlights the diagnosis and therapy for hypoxemia, both pediatric and adult.
PRESENTATION / WEBINAR | Science in 5 series – Episode #33 / Medical oxygen is an essential medicine in the treatment of COVID-19.
GUIDANCE | This NEST-ED Clinical Module has been prepared to help healthcare staff and students understand when and how to use suction pumps in newborn care.
TOOL | This tool from NEST360 provides a clinical scenario for continuous positive airway pressure (CPAP).
TOOL | This tool from NEST360 provides a clinical scenario for oxygen concentrator and flow splitter.
TOOL | This tool from NEST360 provides a clinical scenario for suction pumps.
TOOL | This reference note provides answers to key questions related to providing oxygen therapy as a treatment for COVID-19.
PRESENTATION / WEBINAR | This webinar aims to address the proper management of mechanical ventilation in ARDS due to COVID-19, including ICU basics, intubation and airway management, and more.
PRESENTATION / WEBINAR | Experts from the USAID STAR-UCSF COVID-19 Technical Advisory Group present a webinar and question and answer on optimizing the impact of oxygen scale up.
JOURNAL PUBLICATION | Published in Chest, this study systematically reviewed national COPD guidelines, focusing on worldwide availability, content, context, and quality gaps that may hamper effective implementation.
PRESENTATION / WEBINAR | This webinar focuses on case management and common clinical difficulties within the evaluation of hypoxemia, low-flow oxygen therapy, prone positioning, and noninvasive mechanical ventilation.
JOURNAL PUBLICATION | Published in the Indian Journal of Critical Care Medicine, the objective of this study was to examine systemic oxygen utilization in a case series of patients with this disease.
REPORT | This report summarizes observations from the collected data of a biomedical equipment survey and is intended to help global and national stakeholders understand COVID-19 treatment capacity in Malawi.
REPORT | CHAI supported the Liberia Ministry of Health to conduct an assessment of select facilities to understand current availability of oxygen equipment, as well as facility readiness to provide oxygen therapy.
PRESENTATION / WEBINAR | This video presentation features a panel of pulse oximetry experts sharing essential information on how pulse oximetry works, including that Masimo SET® pulse oximetry is not limited by skin pigmentation.
JOURNAL PUBLICATION | This article in the American Journal of Tropical Medicine and Hygiene outlines pragmatic recommendations for acute respiratory failure and mechanical ventilation in severe COVID-19 patients in LMICs.
JOURNAL PUBLICATION | Published in Tropical Doctor, this prospective observational study looked at the use of oxygen concentrators using solar power in remote health facilities of Papua New Guinea.
ARTICLE | UNICEF is working with governments and partners to find the best solutions to scale up oxygen for each unique country context.
TOOL | This document describes the medical devices required for the clinical management of COVID-19, selected and prioritized according to the latest available evidence and interim guidelines.
JOURNAL PUBLICATION | Published in Journal of Public Health Response, this study describes the response of Bangladesh to tackle the COVID-19 pandemic, particularly given its limited resources.
PRESENTATION / WEBINAR | WHO convened a consultation, held over four meetings, with groups that have proven experience implementing oxygen scale up activities to accelerate oxygen access at the country level.
PRESENTATION / WEBINAR | This is the first lecture in the CMC Vellore COVID Public Lecture Series (COVID PULSE).
REPORT | This report provides a summary of the oxygen supply in Kenya, specifically looking at county capacity, quality of service, and country administration, operations, and safety.
JOURNAL PUBLICATION | This study from PLOS One assessed surge capacity of the Kenyan health system in terms of general hospital and intensive care unit beds during the COVID-19 pandemic.
REPORT | This assessment took stock of the readiness status of health facilities to respond to the COVID-19 pandemic, including an assessment of oxygen supply and delivery systems.
ARTICLE | Availability of oxygen is not currently a standard health system indicator. The EBC coalition has been working to improve the way oxygen and key pneumonia-related indicators are collected and reported.
REPORT | An inventory assessment was conducted in Ethiopia in all public and functional COVID-19 treatment facilities to understand the readiness and capacity of these facilities for COVID-19 case management.
COURSE / TRAINING VIDEO | This training series provides biomedical professionals with remote training, and a platform for discussion and sharing of best practices in caring for COVID-19 patients within low-resource settings.
GUIDANCE | This document aims to clarify the ethical considerations inherent to the COVID-19 pandemic and the provision of emergency care in resource-constrained settings.
GUIDANCE | This page provides different resources to maintain preventive and curative services while also meeting the demand for care of COVID-19 patients.
JOURNAL PUBLICATION | Published in Pediatrics Pulmonology, the study aimed to quantify the regional burden and risks of pediatric pneumonia in Nigeria, and specifically the states of Lagos and Jigawa.
INFORMATION BRIEF | This factsheet outlines the COVID-19 Respiratory Care Response Coordination project to support countries in the development of a comprehensive respiratory care strategy for COVID-19 and beyond.
GUIDANCE | This guidance document is intended for clinicians caring for COVID-19 patients during all phases of their disease (i.e. screening to discharge).
GUIDANCE | This plans lays out containment strategies for India for the COVID-19 pandemic under different transmission scenarios.
GUIDANCE | This page includes resources to help understand the benefits of the procedure and see how pronation therapy can be done safely.
TOOL | This poster provides a summery of the recommendations on the management of patients with COVID-19 and acute respiratory distress syndrome.
PRESENTATION / WEBINAR | This webinar by the All India Institute Of Medical Sciences (AIIMS), New Delhi discusses care protocols in the intensive care unit and ventilation strategies for COVID-19 patients.
PRESENTATION / WEBINAR | This webinar by the All India Institute Of Medical Sciences (AIIMS), New Delhi discusses the modes of ventilation and management strategy as well as weaning from the ventilator and extubation.
JOURNAL PUBLICATION | Published in The Lancet, a conceptual framework is proposed that illustrates the need for hospital readiness and good quality clinical practice for the identification and care of critically ill patients.
GUIDANCE | This document outlines standard operating procedures to ensure optimal utilization of available resources in India, thereby providing appropriate care to all the COVID-19 patients.
TOOL | This guide and Excel tool should be used to administer the SEARO-IMAI oxygen survey at district and regional hospitals.
JOURNAL PUBLICATION | Published in Indian Pediatrics, this study aimed to investigate the status of oxygen monitoring in special newborn care units delivering a model program for retinopathy of prematurity.
JOURNAL PUBLICATION | Published in the Malawi Medical Journal, this study assesses the availability of resources for emergency and critical care in Malawi using data from the Service Provision Assessment.
GUIDANCE | This practical manual outlines how to set up and manage a severe acute respiratory infection (SARI) treatment center and a SARI screening facility in healthcare facilities.
GUIDANCE | This is the first edition of the practical manual to set up and manage a severe acute respiratory infection (SARI) treatment center and a SARI screening facility in healthcare facilities.
GUIDANCE | The purpose of this document is to provide clinical guidance to clinicians working in Tanzania during the COVID-19 pandemic.
JOURNAL PUBLICATION | Published in Systemic Reviews, this study aims to fill a key evidence gap by providing comprehensive estimates of hypoxemia prevalence.
JOURNAL PUBLICATION | This study in eClinical Medicine evaluates the epidemiology of hypoxemia and oxygen use in hospitalized neonates and children in Nigeria.
REPORT | In order to identify questions for future research for IMCI, pneumonia research experts, epidemiologists, and child health specialists from a range of countries participated in a convening in September 2018.
TOOL | Brian Turyabagye is a Ugandan engineer and a co-inventor of a ‘biomedical smart jacket’ which detects pneumonia faster than a doctor.
JOURNAL PUBLICATION | Published in PLoS One, this study describes a nationwide mixed-methods evaluation of private and private-not-for-profit surgical capacity in Uganda, conducted in partnership with the Ministry of Health.
JOURNAL PUBLICATION | Published in Annals of the American Thoracic Society, this study determines if some oxygen overuse in a Rwandan emergency department might coexist with oxygen shortages and underuse for other patients.
JOURNAL PUBLICATION | Published in Annals of the American Thoracic Society, this study assessed a simple education and monitoring intervention to improve care for hypoxemic patients in a Rwandan resource-constrained emergency department.
JOURNAL PUBLICATION | Published in BMJ Open, this study assesses virus-specific hospitalization rates, risk factors for illness severity, and seasonal trends in children hospitalized with acute respiratory infections in Jordan.
JOURNAL PUBLICATION | Published in BMC Pregnancy and Childbirth, this study examined the impact of a package of interventions to 134 health centers, covering 91 rural districts of Ethiopia.
JOURNAL PUBLICATION | Published in The Lancet, this study systematically reviewed the efficacy and safety of liberal versus conservative oxygen therapy in acutely ill adults.
JOURNAL PUBLICATION | Published in Pediatrics, this study demonstrates that the ETAT+ intervention significantly reduced hospital mortality among children under five in Rwanda.
JOURNAL PUBLICATION | Published in World Journal of Surgery, this article describes surgical system reform by the Ethiopian Federal Ministry of Health and the preliminary results of implementation of the SaLTS program.
JOURNAL PUBLICATION | Published in International Journal of Chronic Obstructive Pulmonary Disease, this study analyzed 29 years of data on long-term oxygen therapy (LTOT) in Sweden.
JOURNAL PUBLICATION | Published in Journal of Critical Care, this study describes patient outcomes before and after implementation of an adapted WHO severe sepsis protocol at a community hospital in Haiti.
JOURNAL PUBLICATION | Published in The American Journal of Tropical Medicine and Hygiene, this study aimed to evaluate the microbiological agents linked with hypoxemia in hospitalized children with pneumonia from developing countries.
JOURNAL PUBLICATION | Published in the Nigerian Medical Journal, this study aimed to audit the quality of acute asthma care in two tertiary hospitals in a state in the southwestern region of Nigeria.
JOURNAL PUBLICATION | Published in The European Respiratory Journal, this study evaluated the quality of care of patients with acute exacerbation of COPD and evaluated the change in practice after an educational program.
JOURNAL PUBLICATION | Published in Transactions of the Royal Society of Tropical Medicine and Hygiene, this study investigated predictors of in-hospital mortality and length of stay among adults with CAP in Nigeria.
TOOL | This list highlights the medical devices required to provide the essential reproductive, maternal, newborn and child health interventions defined by existing WHO guidelines and publications.
JOURNAL PUBLICATION | Published in BMJ Open, this study evaluated the effect of home oxygen therapy (HOT) on hospital admissions in chronic obstructive pulmonary disease (COPD) patients.
JOURNAL PUBLICATION | Published in Turkish Thoracic Journal, this study examines the treatment costs of community-acquired pneumonia and the factors influencing hospital expenses in Türkiye.
JOURNAL PUBLICATION | Published in Cochrane Database of Systematic Reviews, this review determines the effectiveness and safety of oxygen delivery methods in the treatment of LRTIs and defines pediatric indications for oxygen.
REPORT | This Service Availability and Readiness Assessment (SARA) in 2014 provides reliable information on health service availability and readiness to support efforts to improve service delivery in Uganda.
JOURNAL PUBLICATION | Published in Journal of Surgical Research, this study found significant disparities in surgical capacity between urban and rural areas in Santa Cruz, Bolivia.
GUIDANCE | The U.S. Food and Drug Administration has developed this guidance document to assist industry in preparing premarket notifications (510(k)s) for pulse oximeters.
JOURNAL PUBLICATION | Published in Respiratory Care, this review focuses on our current knowledge of the end points for supplemental oxygen at home, such as mortality, and highlights areas for future research.
REPORT | This Service Availability and Readiness Assessment (SARA) from 2012 assists the health sector in assessing and monitoring service readiness and capacity at district and health facility levels.
GUIDANCE | These guidelines seek to set achievable standards for trauma treatment services which could realistically be made available to almost every injured person in the world, including for respiratory care.
JOURNAL PUBLICATION | Published in Archives of Childhood Disease, this study assessed the impact of a twofold brief education intervention on the use of oxygen therapy at a rural hospital in Southern Malawi.
JOURNAL PUBLICATION | Published in the World Journal of Surgery, this survey assessed surgical and anesthesia infrastructure in Rwanda as part of a larger study examining low-income African countries.
JOURNAL PUBLICATION | Published in the International Journal of Tuberculosis and Lung Disease, the study describes oxygen concentrator functioning in Malawi and Mongolia as a primary source of oxygen treatment for children.
JOURNAL PUBLICATION | Published in Indian Journal of Anaesthesia, this paper reports on pilot work undertaken in four hospitals in one Indian State to increase patient safety during anesthesia and surgery.
JOURNAL PUBLICATION | Published in BMC Public Health, this review found that improving oxygen systems could significantly reduce childhood pneumonia mortality but faces challenges in affordability and sustainability.
REPORT | The goal of this publication is to share some of the valuable lessons learned by those working on different but overlapping aspects of trauma care worldwide.
TOOL | The WHO Surgical Safety Checklist was developed after extensive consultation aiming to decrease errors and adverse events and increase teamwork and communication in surgery.
JOURNAL PUBLICATION | Published in The International Journal of Tuberculosis and Lung Disease, this study assessed national oxygen availability and use in 12 health facilities in The Gambia.
GUIDANCE | These guidelines provide the knowledge for operational teams to work together effectively to minimize life-threatening complications to surgical patients.
JOURNAL PUBLICATION | Published in Archives of Disease in Childhood, this study aimed to define normal oxygen saturation and to estimate the threshold of hypoxemia for children permanently living at different altitudes.
REPORT | The 2007 Rwanda Service Provision Assessment (RSPA) assessed the strengths and weaknesses of the infrastructure and systems supporting health services in the country.
JOURNAL PUBLICATION | Published in Bulletin of the World Health Organization, this review identifies challenges in improving pneumonia case management in resource-limited settings.
JOURNAL PUBLICATION | Published in Bulletin of the World Health Organization, a study in north-east Tanzania found poor clinical assessment practices in pediatric wards.
JOURNAL PUBLICATION | This study in the Annals of Tropical Pediatrics examined the incidence of hypoxemia, its geographical distribution, epidemiological determinants, and resource availability in several regions of the country.
JOURNAL PUBLICATION | Published in Respiratory Medicine, this study aimed to evaluate the impact of The Danish Oxygen Register on chronic obstructive pulmonary disease (COPD) patients.
JOURNAL PUBLICATION | Published in Seminars in Respiratory and Critical Care Medicine, this study evaluates the quality of care provided to hospitalized patients with community-acquired pneumonia (CAP) from 36 hospitals in 14 countries.
JOURNAL PUBLICATION | Published in the Journal of the Medical Association of Thailand, the purpose of this study was to survey patients, surgical, anesthetic profiles, and determine factors related to adverse events.
JOURNAL PUBLICATION | Published in the Journal of Tropical Pediatrics, this prospective randomized study compared the effectiveness of oxygen treatment by face mask vs. nasal CPAP for pediatric patients with Dengue Shock Syndrome.
JOURNAL PUBLICATION | Published in The Lancet, this article describes a controlled trial of long-term domiciliary oxygen therapy has been carried out in three centres in the United Kingdom.