This library provides a comprehensive set of global and country-specific tools, guidance, and other resources to support oxygen scale-up and long-term respiratory care planning.
JOURNAL PUBLICATION | Published in British Journal of Anesthesia, this study hypothesized that color bias in pulse oximetry results from the optical properties of two LED sources typically used in commercial pulse oximeters.
JOURNAL PUBLICATION | Published in The Lancet Global Health, this study explores contextual factors influencing bCPAP implementation for children in LMICs and to develop a theory on how these factors influence implementation outcomes.
JOURNAL PUBLICATION | Published in Sensors, this study sought to further investigate the root causes of overestimation of arterial oxygen saturation (SpO2) in individuals with darker skin.
JOURNAL PUBLICATION | Published in PLoS Global Public Health, this prospective study evaluated acceptability and feasibility of a multimodal pulse oximeter used by CHWs during their iCCM of childhood illness in rural Burundi.
ARTICLE | The U.S. Food and Drug Administration published new draft guidance aimed at helping improve the accuracy and performance of pulse oximeters across the range of skin pigmentation.
JOURNAL PUBLICATION | Published in Journal of Perinatology, this study assessed if a novel CPAP system is associated with improvement in premature infants in a low-resource setting and if blended oxygen reduced FiO2.
PRESENTATION / WEBINAR | Published by Masimo, this webinar explores the impact of skin pigmentation on pulse oximeter accuracy and introduces advanced technology solutions to improve readings across all skin tones.
JOURNAL PUBLICATION | Published in Engineering and Technology Journal, this study aims to solve the problems of most aftermarket pulse oximeters by developing a cheap, durable, easy to operate, and enhanced reflectance option.
JOURNAL PUBLICATION | Published in Universal Library of Clinical Nursing, this review reports the extent of measurement bias for pulse oximeters, describes its clinical importance, and discusses approaches to eliminating it.
JOURNAL PUBLICATION | Published in IEEE, this study investigates the impact of melanin concentration on the accuracy of oxygen saturation (SpO2) estimation using reflective photoplethysmography (PPG) measurements.
JOURNAL PUBLICATION | Published in Heart, this study aimed to compare standard manual oxygen administration with automated oxygen administration (AOA) using the O2matic device.
JOURNAL PUBLICATION | Published in Journal of Clinical Medicine, this study compares the quality of oxygenation from automated ventilation provided by INTELLiVENT-Adaptive Support Ventilation vs. ventilation that is not automated.
JOURNAL PUBLICATION | This paper proposes a conceptualization of a particular delivery model that takes a broader approach than the traditional oxygen procurement and delivery – ‘Outsourced Oxygen-to-the-Bedside’ (O2B).
JOURNAL PUBLICATION | Published in Pediatric Pulmonology, this study assesses families’ perceptions of consumer-grade oxygen saturation monitors, highlighting usage patterns and the need for education.
JOURNAL PUBLICATION | Published in Annals of the American Thoracic Society, this paper describes how this rule recognizes that pulse oximeters are less reliable on dark skin pigmentation and needs to be addressed.
JOURNAL PUBLICATION | Published in Journal of Hospital Medicine, this study found that most continuous pulse oximetry monitoring in stable bronchiolitis patients was done without clinical justification.
JOURNAL PUBLICATION | Published in Journal Medical Internet Research, this study explores the impact of social media, specifically X, on increasing awareness of racial disparities in the accuracy of pulse oximetry.
JOURNAL PUBLICATION | Published in World Journal of Clinical Pediatrics, this study evaluates the advantages, limitations, and challenges of pulse oximetry in clinical practice, as well as proposes recommendations to optimize its use.
JOURNAL PUBLICATION | Published in Respiratory Care, this article summarizes the current status of automated oxygen administration systems, and their potential to improve precision in oxygen delivery.
JOURNAL PUBLICATION | Published in Cureus, this paper reviews the history and evolution of pulse oximeters, the scientific laws behind oximetry, and the limitations of pulse oximetry, especially related to skin pigmentation.
REPORT | This report highlights significant advancements in oxygen production, distribution, and delivery, driven by the COVID-19 pandemic, which are crucial for improving health care in LMICs.
JOURNAL PUBLICATION | Published in The Lancet Global Health, the study demonstrated that bCPAP therapy reduced treatment failure and mortality in children with severe pneumonia and hypoxemia in Ethiopian hospitals.
ARTICLE | UNICEF has handed over Nigeria’s first fully solar-powered pressure swing adsorption oxygen plant to the Jericho Specialist Hospital, Ibadan in Oyo State.
JOURNAL PUBLICATION | Published in Pediatric Pulmonology, this study evaluates the use of bCPAP in improving outcomes and reducing mortality in children with severe pneumonia and hypoxemia in Bangladesh.
JOURNAL PUBLICATION | Published in EBioMedicine, this study evaluated eleven popular fingertip pulse oximeters using the U.S. FDA Guidance (2013) and ISO Standards (2017) in 34 humans with diverse skin pigmentation.
JOURNAL PUBLICATION | Published in Indian Journal of Anaesthesia, this study found that PSA plants are the most cost-effective source of medical oxygen when used at full capacity with electricity.
TOOL | This mechanism aggregated demand for oxygen compressor service kits across LMICs and fulfilled demand in a timely manner using advanced purchases of RIX Industries oxygen compressor service kits.
JOURNAL PUBLICATION | Published in Journal of Global Health, this study assesses the feasibility of using locally made bCPAP oxygen therapy for adults with severe pneumonia and hypoxemia.
JOURNAL PUBLICATION | Published in PLoS Digital Health, this article investigates how digital determinants of health contribute to bias in health technologies and their potential impact on healthcare equity.
JOURNAL PUBLICATION | Published in The Lancet Respiratory Medicine, this article calls for a revision of WHO’s pneumonia guidelines in light of new findings from Bangladesh.
JOURNAL PUBLICATION | Published in Journal of Patient Safety, this article highlights the rise in hospital fire outbreaks during the COVID-19 pandemic in LMICs and calls for enhanced fire prevention measures.
JOURNAL PUBLICATION | Published in BMJ Global Health, this article emphasizes the challenges in bridging the gap between prioritizing health services for universal health coverage (UHC) and implementing them effectively.
JOURNAL PUBLICATION | Published in the American Journal of Epidemiology, this study analyzed pulse oximeter accuracy on darker skin pigmentation and its association with COVID-19 treatment outcomes in Northern California.
JOURNAL PUBLICATION | Published in American Journal of Respiratory and Critical Care Medicine, this article describes how innovations in oxygen delivery should incorporate all aspects of the oxygen system yet be frugal.
JOURNAL PUBLICATION | Published in Journal of Chemical Education, this study highlights the role of knowledge transfer in the development of oxygen concentrators during the COVID-19 pandemic.
JOURNAL PUBLICATION | Published in Pediatric Pulmonology, this article reviews the use of bbCPAP devices in low-resource settings, highlighting how such devices can reduce neonatal mortality despite limited resources.
TOOL | The Global Fund is partnering with UNICEF to source oxygen products. The current product list, including pricing and a link to the technical specifications, can be found in this document.
ARTICLE | WHO Nepal handed over a solar power generation system to Province Hospital, Surkhet to power their PSA plant and support other medical and IT equipment.
JOURNAL PUBLICATION | Published in JAMA, this Viewpoint discusses how some pulse oximeters can provide incorrect oxygen saturation data for dark-skinned patients compared with light-skinned patients.
GUIDANCE | The publication provides a comprehensive update on the status and key actions needed for providing reliable, modern energy to health-care facilities in low- and middle-income countries.
DATA DASHBOARD | This World Bank dashboard highlights exports by countries from 2022, including medical ventilators, continuous positive airway pressure (CPAP), bilevel positive airway pressure (BiPAP), and oxygen concentrators.
TOOL | India procured numerous PSA plants during COVID-19 however many are underutilized due to electricity needs. Creating a low-cost power alternative is pertinent for their sustainability in the country.
JOURNAL PUBLICATION | Published in Psychology, Health & Medicine, this study examines how electrification in LMICs improves healthcare outcomes, particularly in antenatal care, emergency services, and medical supply reliability.
REPORT | Published by the AtMF and Chatham House, this report summarizes the roundtable discussions on sustaining long-term LOX access in LMICs, focusing on funding, production, and public-private collaboration.
REPORT | This NEST360 report outlines a compendium of newborn healthcare technologies, both commercially available and in development, suitable for use in resource-limited settings.
JOURNAL PUBLICATION | Published in Cochrane Database of Systematic Reviews, this study evaluates nasal masks and prongs as interfaces for CPAP in preterm infants, comparing their effects on treatment success, nasal trauma, etc.
TOOL | This sheet is a living document and is being populated with specifications of oxygen concentrators.
JOURNAL PUBLICATION | Published in Disaster Medicine and Public Health Preparedness, this study found that regulatory bottlenecks in India’s medical oxygen supply chain worsened during the COVID-19 crisis.
JOURNAL PUBLICATION | Published in Tropical Medicine & International Health, this study evaluates the cost-effectiveness of adding pulse oximetry to primary care for acute respiratory infection management in rural Thailand.
TOOL | The Global Fund is partnering with UNICEF to source oxygen products. The current product list, including pricing and a link to the technical specifications, can be found in this document.
JOURNAL PUBLICATION | Published in Journal of Clinical Medicine, this trial assesses BCPAP versus low-flow oxygen therapy for treating childhood pneumonia and hypoxemia in Ethiopia.
JOURNAL PUBLICATION | Published in BMC Medicine, this study systematically reviewed the effects of skin pigmentation on the SpO2 accuracy by pulse oximetry compared with the gold standard SaO2 measured by CO-oximetry.
GUIDANCE | This guide highlights evaluation results and provides 12 opportunities of designing oxygen concentrators, humidifier bottles, and flow splitters to address the oxygen gap in healthcare settings in LMICs.
GUIDANCE | This publication provides an overview of the process of evaluation, adoption, and acquisition of PSA oxygen plants by comparing technical, administrative, and financial aspects of this technology.
TOOL | The NEST360 qualified technologies are a list of newborn care technologies best suited for use in low-resource setting hospitals, including being effective, affordable, rugged, and simple to use.
COURSE / TRAINING VIDEO | This course covers pulse oximetry use in the time of COVID-19.
JOURNAL PUBLICATION | Published in International Journal of Pharmaceutical Sciences and Research, this study focuses on the devices, including ventilators, which require regulations but still lack the quality check points.
TOOL | UNICEF, in collaboration with NEST360 and the Oxygen CoLab, is driving the development of a fit-for-purpose Resilient Oxygen Concentrator for low-resource settings.
TOOL | Lifebox has worked with its global network of partners to distribute pulse oximeters across 53 countries for the ongoing care of COVID-19 patients as well as developed multi-language educational materials.
JOURNAL PUBLICATION | Published in Health and Technology, this article aims to create awareness about commonly used medical devices during the COVID-19 pandemic and to survey trust in home usable devices in India.
JOURNAL PUBLICATION | Published in Indian Journal of Critical Care Medicine, this study compared PEAO rates in nasotracheal vs orotracheal intubation in critically ill children.
JOURNAL PUBLICATION | Published in Sante Publique, this article investigates the functionality of oxygen concentrators in hospitals in North Kivu, DRC, and emphasizes the need for improved maintenance and training.
JOURNAL PUBLICATION | Published in BMJ Open Respiratory Research, this study found that the SpO2 threshold for hypoxemia in well children from Bangladesh was higher than the conventional <90%.
JOURNAL PUBLICATION | The World Federation of Societies of Anesthesiologists (WFSA) has developed the “WFSA—Minimum Capnometer Specifications 2021”, which are published in Anesthesia & Analgesia.
ARTICLE | UNICEF has developed an innovative Oxygen Plant-in-a-Box package in response to COVID-19 to help countries rapidly increase their oxygen producing capacity. This provides an example from Uganda.
TOOL | This clinical job aid from NEST360 provides an overview of an Acare suction pump, including assessment and preparation as well as repair and maintenance of the device.
TOOL | This clinical job aid from NEST360 provides an overview of an AirSep oxygen concentrator, including assessment and preparation as well as repair and maintenance of the device.
TOOL | This clinical job aid from NEST360 provides an overview of an Aspeed suction pump, including assessment and preparation as well as repair and maintenance of the device.
TOOL | This clinical job aid from NEST360 provides an overview of a Bistos pulse oximeter, including assessment and preparation as well as repair and maintenance of the device.
TOOL | This clinical job aid from NEST360 provides an overview of a bubble CPAP device.
TOOL | This clinical job aid from NEST360 provides an overview of a Canta oxygen concentrator, including assessment and preparation as well as repair and maintenance of the device.
TOOL | This clinical job aid from NEST360 provides an overview of a flow splitter, including assessment and preparation as well as repair and maintenance of the device.
TOOL | This clinical job aid from NEST360 provides an overview of a LifeBox pulse oximeter, including assessment and preparation as well as repair and maintenance of the device.
COURSE / TRAINING VIDEO | These NEST360 training videos demonstrate model-specific equipment setup, use, and maintenance and are used as training aids in clinical and technical training.
JOURNAL PUBLICATION | Published in BMC Health Services Research, this study showed that using oxygen concentrators in Fiji’s hospitals would reduce costs by 55% compared to using oxygen cylinders alone.
TOOL | This document, featuring common noninvasive oxygen delivery devices, is part of a set of tools that can be locally modified to train health providers in respiratory care.
JOURNAL PUBLICATION | Published in JAMA Open Network, this study reviewed the cost-effectiveness of solar-powered oxygen delivery for young children with severe pneumonia in low-resource settings.
TOOL | This tool from NEST360 provides a technical scenario for a bubble CPAP device.
TOOL | This tool from NEST360 provides a technical scenario for a flow splitter.
TOOL | This tool from NEST360 provides a technical scenario for an oxygen concentrator.
TOOL | This tool from NEST360 provides a technical scenario for a pulse oximeter.
TOOL | This tool from NEST360 provides a technical scenario for a suction pump.
JOURNAL PUBLICATION | Published in Journal of Pharmaceutical Policy and Practice, this paper reviews key entities involved in regional and continental harmonization of medicines regulation and the milestone of the African Medicines Agency.
REPORT | This report presents findings of the registration status of tracer MNCH medicines and the functionality of regulatory agencies with respect to legal provisions, organization and resources, and registration processes.
JOURNAL PUBLICATION | Published in Archives of Disease in Childhood, this study explores the feasibility of splitting a bubble CPAP assembly using a T-piece splitter in a simulation model.
JOURNAL PUBLICATION | Published in Journal of Biosciences and Medicines, this article explores the occurrence of “happy hypoxia” in COVID-19 patients in Kinshasa, highlighting the importance of early detection.
JOURNAL PUBLICATION | To respond to inflated costs and export restrictions on medical equipment, Mercedes HPP worked with key experts to produce a simple, mechanical noninvasive respiratory device to deliver CPAP.
JOURNAL PUBLICATION | Published in Tropical Doctor, this prospective observational study looked at the use of oxygen concentrators using solar power in remote health facilities of Papua New Guinea.
JOURNAL PUBLICATION | Published in Prehospital and Disaster Medicine, this study explores the feasibility of mechanical ventilation with room air in ARDS models, suggesting its potential use in low-resource settings.
JOURNAL PUBLICATION | Published in the Journal of Global Health, this study describes the development and field testing of two oxygen supply solutions suitable for the realities of health facilities in LMICs.
GUIDANCE | This document specifies requirements for the basic safety and essential performance of an oxygen concentrator in combination with its accessories.
ARTICLE | This project explored the possibilities of producing concentrated medical-grade oxygen with direct solar power during daytime and store it as compressed gas for night-time use.
JOURNAL PUBLICATION | Published in the Pan African Medical Journal, study assesses the implementation of a multi-center, comprehensive hospital-based bCPAP program in three states of Nigeria using a low-cost device.
REPORT | This dashboard illustrates the evolution of solar PV module cost by data source between 1970 and 2020.
TOOL | UNICEF has developed an Excel-based tool to help stakeholders plan their oxygen supply system.
COURSE / TRAINING VIDEO | This is an instructional video to show the use of a LifeBox pulse oximeter in the context of the COVID-19 pandemic.
COURSE / TRAINING VIDEO | This instructional video demonstrates how to use a pulse oximeter in the COVID-19 pandemic.
TOOL | In collaboration with UNICEF, NEST360 is driving the development of target product profiles for newborn care in low-resource settings.
JOURNAL PUBLICATION | Published in BMJ Open, this study revealed that CPAP is used in neonatal units across India but faces significant infrastructure and training gaps, with high case fatality rates and complications.
JOURNAL PUBLICATION | Published in Breathe (Sheffield, England), this article reviews oxygen devices and delivery systems, including concentrators and cylinders, and discusses their indications, benefits, and limitations for managing respiratory failure and hypoxemia.
JOURNAL PUBLICATION | Published in Paediatrics and International Child Health, this study designed, produced, and trialed an appropriate low-cost bCPAP machine in Nigeria which is functionally effective and safe.
JOURNAL PUBLICATION | Published in Paediatric International Child Health, this review identified key components for designing bubble CPAP circuits for children in low-resource settings.
JOURNAL PUBLICATION | Published in Paediatric International Child Health, this commentary article contextualizes the importance of research into two treatment modes proposed in low-income countries: CPAP and humidified HFNC.
JOURNAL PUBLICATION | Published in BMC Health Services Research, this study found that bCPAP required more time from healthcare workers than low-flow nasal oxygen in treating child pneumonia in Malawi.
JOURNAL PUBLICATION | Published in BMJ Open, this study evaluates the feasibility of pediatric pulse oximetry for pneumonia in Malawi and Bangladesh, identifying barriers and calling for improvements in infrastructure.
JOURNAL PUBLICATION | Published in BMJ Open, this study found that bCPAP is a cost-effective intervention for treating severe pediatric pneumonia in Malawi, with an incremental cost-effectiveness ratio of US$12.88 per DALY averted.
JOURNAL PUBLICATION | Published in Cost Effectiveness and Resource Allocation, this study evaluates the impact of emerging health innovations on maternal, newborn, and child health to save lives by 2030.
GUIDANCE | ISO 80601-2-61:2017 applies to the basic safety and essential performance of pulse oximeter equipment intended for use on humans.
JOURNAL PUBLICATION | Published in Anaesthesia, this study determined whether the introduction of pulse oximetry with training was feasible and could reduce the incidence of oxygen desaturation during anesthesia in Malawi.
JOURNAL PUBLICATION | Published in Anaesthesia, this article highlights the introduction of Lifebox pulse oximeters combined with appropriate training in Malawi.
JOURNAL PUBLICATION | Published in the International Journal of Tuberculosis and Lung Disease, this article examines the success and impact of an uninterrupted oxygen supply system in a Gambian hospital over eight years.
JOURNAL PUBLICATION | Published in Anesthesia & Analgesia, this study evaluated the accuracy of 6 low-cost finger pulse oximeters during stable arterial oxygen saturations (SaO2) between 70% and 100% in 22 healthy subjects.
MULTIMEDIA | The Safe Newborn bCPAP Project will address the lack of access in low-resource settings to safe and affordable treatment for respiratory distress syndrome.
JOURNAL PUBLICATION | Published in Paediatric International Child Health, this study demonstrates the feasibility and effectiveness of bCPAP in treating acute respiratory failure in Malawian children.
TOOL | This table shows the landscape of commercially available stationary and portable oxygen concentrators and related devices.
GUIDANCE | This document provides guidance to developers and manufacturers on the key performance requirements and potential design for a reliable, robust, and scalable oxygen concentrator.
JOURNAL PUBLICATION | Published in Archives of Diseases in Childhood, this study evaluated the impact of installing a hybrid solar power system on in-patient pediatric mortality at a district hospital in Sierra Leone.
JOURNAL PUBLICATION | Published in Archives of Disease in Childhood, this study examines the fear of oxygen therapy for children in Malawi, identifying key factors influencing acceptance and suggesting strategies to improve uptake.
JOURNAL PUBLICATION | Published in Journal of Clinical Anesthesia, this article analyzes the root causes of hospital fires in India and provides recommendations for preventing these incidents, with a focus on oxygen safety.
JOURNAL PUBLICATION | Published in Anaesthesia, this study evaluates seven models of oxygen concentrators for use in resource-limited countries, identifying key performance issues under high temperature and humidity conditions.
GUIDANCE | The U.S. Food and Drug Administration has developed this guidance document to assist industry in preparing premarket notifications (510(k)s) for pulse oximeters.
JOURNAL PUBLICATION | Published in PLoS One, this study describes the design and technical evaluation of a new, rugged bCPAP system that can be made in small volume for approximately $350.
TOOL | A new oxygen concentrator technology uses electrolytic oxygen transfer through a ceramic, monolithic wafer—capable of producing high-purity (>99.9%) pressurized (200 psig) oxygen without a mechanical compressor.
JOURNAL PUBLICATION | This review presents and compares four different medical oxygen system configurations across a wide range of criteria relevant to low-resource settings.
ARTICLE | Published in the 2011 IEEE Global Humanitarian Technology Conference, this study explores the use of oxygen concentrators as a solution to oxygen shortages in developing countries.
GUIDANCE | Published by Acare Technology Co., Ltd., this manual outlines the usage, setup, and safety guidelines for the AH-M1 handheld pulse oximeter, including features like alarms and maintenance procedures.
JOURNAL PUBLICATION | Published in Anaesthesia, this article discusses the international anaesthesia quality improvement project focused on expanding the availability and use of pulse oximetry in hospitals across low-resource settings.
JOURNAL PUBLICATION | Published in Journal of Clinical Engineering, this survey evaluates 11 oxygen concentrator models for use in tropical countries, identifying the most effective models based on performance, cost, etc.
JOURNAL PUBLICATION | Published in Bulletin of the World Health Organization, this article details the successful implementation of oxygen concentrators in Malawi’s pediatric wards to combat hypoxemia in severely ill children.
JOURNAL PUBLICATION | Published in Bulletin of the World Health Organization, this study highlights the challenges faced by a Gambian hospital after receiving incompatible oxygen concentrators.
GUIDANCE | Published by the UK Department for International Development, this guide provides a detailed process for procuring and commissioning healthcare technology, covering preparation, procurement, distribution, and installation.
JOURNAL PUBLICATION | Published in Respirology, this study found that chronic obstructive pulmonary disease imposes a significant economic burden on Japan, with total costs amounting to 805.5 billion yen annually.
JOURNAL PUBLICATION | Published in Wilderness Environmental Medicine, this study highlights the use of oxygen concentrators in remote high-altitude hospitals, demonstrating significant cost savings and reliable oxygen delivery compared to traditional cylinders.
JOURNAL PUBLICATION | Published in The Lancet, this article details a field trial in Upper Egypt that tests the effectiveness of oxygen concentrators in small rural hospitals.
JOURNAL PUBLICATION | Published in Annals of Emergency Medicine, this study showed that clinical evaluation alone was insufficient to detect low oxygen saturation in pediatric patients.
JOURNAL PUBLICATION | Published in the British Journal of Anaesthesia, this article describes the development of a suitable anesthetic machine for underdeveloped contexts and the match of a suitable oxygen concentrator.
JOURNAL PUBLICATION | Published in the Canadian Journal of Anaesthesia, this study assessed the features of a Kinox-2 concentrator at the Military Hospital in Kathmandu.
JOURNAL PUBLICATION | Published in Tropical Doctor, this study looks at the use of oxygen concentrators in a remote hospital in Zaire, now the Democratic Republic of the Congo.
COURSE / TRAINING VIDEO | In this course, biomedical engineers with a strong background in biomedical engineering or electronics will be given a refresher on oxygen concentrators.
TOOL | This form allows organizations to report their donations for COVID-19.
TOOL | This resource provides a list of various makes and models of existing pulse oximeters.
TOOL | UNICEF worked with industry to rapidly develop an innovative emergency solution: the Oxygen Plant-in-a-Box—a fully functional pressure swing adsorption (PSA) oxygen plant.
TOOL | This website provides the oxygen technology from Fritz Stephan GmbH – tailor-made ventilation solutions for premature infants, children, and adults.
TOOL | The OxBox device allows for rapid scaling up oxygen delivery capacity in low-resource settings by mitigating two main barriers: electricity and cost-effectiveness.
REPOSITORY / TOOLKIT | This oxygen library by the Oxygen Alliance includes videos, comprehensive service manuals, and other information on every oxygen concentrator the Alliance has analyzed in the past.
TOOL | NASA’s Jet Propulsion Laboratory designed an FDA qualifiable ventilating device that can serve a targeted subset of the patient population suffering from acute respiratory distress syndrome caused by COVID-19.
TOOL | This presentation highlights the Bioforge Oxysaver, which was developed as a more affordable product for LMICs, compared to the Demand Oxygen Delivery Systems (DODS) currently available.
DATA DASHBOARD | This National Medical Oxygen Grid (NMOG) is a cellphone-based app to help hospitals and health officials keep track of where medical oxygen is needed and where supplies are plentiful.
JOURNAL PUBLICATION | Published in Public Health Action, this study assesses the electronic dashboard for oxygen monitoring and stockout prevention implemented during the COVID-19 pandemic across 12 hospitals in Lesotho.
TOOL | Open Oximetry has created a simple process to help build a custom pulse oximetry infographic.
JOURNAL PUBLICATION | Published in The Lancet Global Health, this randomized trial compared automated versus manual oxygen control for preterm infants receiving CPAP in southwest Nigeria.
JOURNAL PUBLICATION | Published in The Lancet Global Health, this paper urges WHO, governments, ministries of health, and funders to implement these 5 recommendations to strengthen the biomedical engineering profession.
JOURNAL PUBLICATION | Published in The Lancet Global Health, this Comment highlights grassroots interventions that show the potential of local capacity to strengthen medical oxygen security in LMICs.
JOURNAL PUBLICATION | Published in The Lancet Global Health, the paper emphasizes an urgent need for more investment in health systems and research to develop sustainable and safe access to medical oxygen.
JOURNAL PUBLICATION | The Lancet Global Health Commission on medical oxygen security aimed to synthesize available evidence and produce actionable recommendations. This article highlights the results of the Commission’s work.
GUIDANCE | This website outlines treatment guidelines for use of oxygen after COVID-19, including mechanical insufflator-exsufflator (MIE), home ventilator treatment, and oxygen therapy at home.
JOURNAL PUBLICATION | There is a precedent: over recent decades, the pharmaceutical industry has increasingly recognized its pivotal role in global health and acknowledged the importance of expanding access to medicine globally.
JOURNAL PUBLICATION | Published in The Lancet Global Health, this case study outlines a national medical oxygen grid in India, which aims to ensure high-quality medical oxygen supply in routine and surge scenarios.
JOURNAL PUBLICATION | Published in The Lancet Global Health, this case study focuses on the current state of medical oxygen supply chain at multiple levels of the Ugandan health system.
JOURNAL PUBLICATION | Published in medRxiv, this randomized crossover trial evaluated the feasibility and preliminary effects of continuous automated oxygen titration in the homes of patients on long-term oxygen therapy for COPD.
JOURNAL PUBLICATION | Published in BMJ Global Health, this study examines whether stabilization rooms equipped with pulse oximetry and oxygen alongside HCW training improved quality of care for children with pneumonia in Nigeria.
JOURNAL PUBLICATION | Published in BMJ Global Health, this study examines how stabilization rooms under the INSPIRING-Lagos project improved pulse oximetry practices, for whom, and in what contexts in Nigeria.
REPORT | This investigation examined five innovative technical options spanning facility design, material, and component sourcing, and installation that could help alleviate barriers to install piping for medical oxygen.
JOURNAL PUBLICATION | Published in BMC Pulmonary Medicine, this study examined the communication of oxygen management plans in the electronic health record (EHR), and their consistency with patient-reported long-term oxygen therapy (LTOT) use.
GUIDANCE | This updated guidance on medical device donation includes new evidence, new references on considerations for medical device solicitation and provision, risks associated with inappropriate donations, etc.
JOURNAL PUBLICATION | Published in the Pan African Medical Journal, this paper examines the current challenges and advancements in the oxygen supply chain within LMICs, focusing on availability, infrastructure, and usage.
REPORT | This final report provides an overview of the audit of USAID’s Oxygen Ecosystem Program for COVID-19 Relief using American Rescue Plan Act of 2021 funding.
ARTICLE | The Zambian Ministry of Health worked with CHAI to install a new liquid oxygen tank at the Levy Mwanawasa University Teaching Hospital.
REPORT | This report highlights AirLiquide’s challenges, successes, and progress in 2023.
JOURNAL PUBLICATION | Published in Cochrane Database of Systematic Reviews, this review found that automated oxygen delivery systems likely increase time spent within the target SpO2 range compared to manual oxygen control.
INFORMATION BRIEF | Between 2021 and 2023, PATH undertook a series of analyses to better characterize the oxygen generation plant market and its ownership costs.
JOURNAL PUBLICATION | Published in BMC Health Services Research, this review explored the acceptability of health technology innovations in sub-Saharan Africa, revealing a lack of consistent frameworks.
JOURNAL PUBLICATION | Published in Archives of Community Medicine and Public Health, this paper shares the experience of Chad in its efforts to improve the availability of oxygen for the management of respiratory...
JOURNAL PUBLICATION | Published in PLoS Global Public Health, this study aims to assess the value of improved access and use of oxygen concentrators and cylinders during the COVID-19 pandemic in India.
JOURNAL PUBLICATION | Published in PLoS Global Public Health, this study explores the usability of pulse oximeters for community health and primary care workers in Cambodia, Ethiopia, South Sudan, and Uganda.
JOURNAL PUBLICATION | Published in The Lancet, this study investigated the feasibility of regenerating old zeolite for use in oxygen concentrators.
REPORT | This report tracks six global gas companies’ initiatives to increase access and provides insights into what they can do to supply LOX during emergencies and for day-to-day needs of LMICs.
ARTICLE | To address recruitment challenges in Nigeria and improve medical oxygen supplies, CHAI collaborated with the Biomedical Engineering Training Institute to conduct a national TOT for biomedical engineers.
JOURNAL PUBLICATION | Published in The Lancet Global Health, this article introduces The Lancet Global Health Commission on Medical Oxygen Security, which seeks to close critical gaps in oxygen access, especially in LMICs.
JOURNAL PUBLICATION | Published in Journal of Pharmaceutical Sciences, this review evaluates the updated European Medical Device Regulations and their global impact, emphasizing stricter compliance requirements post-COVID-19.
JOURNAL PUBLICATION | Published in COPD, this observational study assessed whether a new hybrid flow meter reduces oxygen expenditure, is well accepted in a hospital setting, and improves patient comfort during oxygen therapy.
JOURNAL PUBLICATION | Published in Medicine, Conflict and Survival, this study aimed to assess the effectiveness of solar powered oxygen at Hanano General Hospital in Dusamareb, Galmudug State, Somalia, in a conflict-affected region.
JOURNAL PUBLICATION | Published in the Indian Journal of Pediatrics, this review focuses on sources of medical oxygen like cryogenic oxygen plants, pressure swing adsorption, oxygen concentrators, and oxygen cylinders.
ARTICLE | In January 2021, Somalia’s Ministry of Health, supported by the WHO Innovation Hub and the WHO Country Office, piloted a solar-powered oxygen delivery system.
JOURNAL PUBLICATION | Published in Sensors (Basel, Switzerland), this review aims to study the literature that assesses the influence of skin pigmentation on the accuracy of pulse oximeters.
JOURNAL PUBLICATION | Published in Journal of Global Health, this study assessed pulse oximetry performance of different types of assessors in inpatient settings after an update to the existing IMCI package in Bangladesh.
JOURNAL PUBLICATION | Published in Indian Journal of Critical Care Medicine, this article highlights the problems with donated medical equipment.
JOURNAL PUBLICATION | Published in JAMA Network Open, this study assesses the financial burden of using oxygen concentrators for home oxygen therapy, emphasizing significant variations in electricity costs across U.S. states.
JOURNAL PUBLICATION | Published in Journal of Global Health, this scoping review assesses oxygen delivery systems for adults in Sub-Saharan Africa, identifying challenges and recommending solutions for improving health systems.
ARTICLE | This article highlights a country case study from Somalia from the 2021 progress report on the implementation of the Global Action Plan for Healthy Lives and Well-being for All (GAP).
PRESENTATION / WEBINAR | To maximize oxygen delivery, a device has been developed to detect patient inhalation and deliver oxygen during only the inspiratory phase, which can allow cylinders to last 2-3x longer.
JOURNAL PUBLICATION | Published in Acta Paediatrica, this study identifies whether Ethiopia’s health extension workers adhere to required guidelines while assessing children under 5 with cough or difficulty breathing.
JOURNAL PUBLICATION | Published in Science of The Total Environment, this study evaluates the environmental and economic impacts of three medical oxygen supply systems used in Polish hospitals during the COVID-19 pandemic.
TOOL | This tool from NEST360 provides a clinical scenario for continuous positive airway pressure (CPAP).
TOOL | This tool from NEST360 provides a clinical scenario for oxygen concentrator and flow splitter.
TOOL | This tool from NEST360 provides a clinical scenario for suction pumps.
JOURNAL PUBLICATION | Published in The Lancet Respiratory Medicine, this study reviews global efforts to ensure an adequate medical oxygen supply during the COVID-19 pandemic, highlighting challenges and innovations.
JOURNAL PUBLICATION | Published in Tropical Doctor, this study explored the views of rural health workers in Papua New Guinea on the impact of a program to improve their oxygen delivery systems.
JOURNAL PUBLICATION | Published in Journal of the Indian Institute of Science, this article provides an overview of the emergence of healthcare information technology globally and recommends policy intervention for the Indian context.
REPOSITORY / TOOLKIT | The Ventilator Training Alliance provides a library of training and product resources for medical professionals.
JOURNAL PUBLICATION | Published in African Journal of Primary Health Care and Family Medicine, this article highlights different technologies used in Africa to combat COVID-19 oxygen shortages and how to leverage them long-term.
TOOL | This flowchart lays out use of pulse oximetry in the decision-making process for COVID-19 treatment with oxygen therapy.
JOURNAL PUBLICATION | Published in Journal of Pediatrics, this review found that HFNC reduced treatment failure in children with mild hypoxemia, but nCPAP was more effective for infants with severe hypoxemia.
JOURNAL PUBLICATION | Published in The Lancet Respiratory Medicine, this study found that bCPAP did not improve survival rates in high-risk children with severe pneumonia in Malawi compared to low-flow oxygen.
TOOL | Brian Turyabagye is a Ugandan engineer and a co-inventor of a ‘biomedical smart jacket’ which detects pneumonia faster than a doctor.
JOURNAL PUBLICATION | Published in PLoS One, this study tested a low-pressure oxygen storage system to ensure continuous oxygen delivery during power outages in Uganda.
JOURNAL PUBLICATION | Published in Respiratory Care, the aim of this study was to understand perceived limitations that patients with chronic obstructive pulmonary disease (COPD) experience in using long-term oxygen therapy (LTOT) devices.
JOURNAL PUBLICATION | Published in Respiratory Care, this retrospective study looked at the implementation of an open-design oxygen mask 12 months before and 12 months after implementation.
JOURNAL PUBLICATION | Published in Trials, this study protocol outlines a trial designed to improve oxygen therapy for children and neonates in Nigerian hospitals through better equipment and healthcare training.
INFORMATION BRIEF | This summary document highlights PATH’s proposed inclusion of oxygen as a medical gas on the WHO Model List of Essential Medicines (for Children) to clarify its importance as a medicine.
JOURNAL PUBLICATION | Published in Paediatrics International Child Health, this article examines a quality improvement project in rural Papua New Guinea hospitals to enhance pediatric and neonatal care, including oxygen therapy.
JOURNAL PUBLICATION | Published in PLoS One, the use of a low-cost bCPAP system in Malawi showed a significant improvement in survival rates for neonates with respiratory distress compared to standard care.
JOURNAL PUBLICATION | This study was conducted to ascertain the economy achieved by employing a small portable oxygen concentrator for oxygen therapy to improve functionality of a surgical unit in remote environments.
JOURNAL PUBLICATION | Published in Respiratory Care, this article emphasizes that contracted vendors can deliver oxygen to alternate care facilities in disaster areas, in the form of concentrators, gas cylinders, or liquid oxygen.
JOURNAL PUBLICATION | Published in Ontario Health Technology Assessment Series, this study found that COPD smoking cessation programs were cost-effective, while multidisciplinary care and pulmonary rehabilitation were also beneficial but costly.
JOURNAL PUBLICATION | Daily temperature and humidity data were collected at a health center in The Gambia, where a battery system has been installed as back-up power for a medical oxygen system.
JOURNAL PUBLICATION | Published in the International Journal of Tuberculosis and Lung Disease, the study describes oxygen concentrator functioning in Malawi and Mongolia as a primary source of oxygen treatment for children.
JOURNAL PUBLICATION | Published in Indian Journal of Anaesthesia, this paper reports on pilot work undertaken in four hospitals in one Indian State to increase patient safety during anesthesia and surgery.
JOURNAL PUBLICATION | Published in Bulletin of the World Health Organization, this study compares oxygen supply options for health facilities in The Gambia and presents a decision-making algorithm for oxygen systems.
JOURNAL PUBLICATION | Published in the American Journal of Hospice and Palliative Care, this study presents a brief analysis of the cost of operating an oxygen concentrator from the perspective of the patient.
JOURNAL PUBLICATION | Published in the International Journal for Tuberculosis and Lung Disease, this study explored the use of oxygen concentrators compared to cylinders to treat children in a hospital in Ndioum, Senegal.
JOURNAL PUBLICATION | Published in the Annals of Tropical Pediatrics, this study explored the 3-year experience of using an oxygen concentrator in a Nigerian newborn unit and economic appraisal of its effectiveness.
JOURNAL PUBLICATION | Published in the Canadian Journal of Anaesthesia, this study aims to review the efficacy and reliability of oxygen concentrators used over the last six years in Nepal.
JOURNAL PUBLICATION | Published International Journal of Tuberculosis and Lung Disease, this paper compares the costs incurred using oxygen cylinders with a solar operated oxygen concentrator in a rural Gambian setting.
JOURNAL PUBLICATION | Published in European Respiratory Journal, this trial shows that while liquid oxygen therapy is more costly than concentrator treatment, it provides substantial improvements in quality of life for chronic patients.
JOURNAL PUBLICATION | Published in Canadian Journal of Anaesthesia, this study highlights the resource challenges in delivering anesthesia at Barbados’ Queen Elizabeth Hospital.
JOURNAL PUBLICATION | The oxygen supply in West Africa has been irregular for decades. Korle Bu Hospital, Accra, Ghana has been producing its own oxygen within the hospital since 1986.
TOOL | Published by the Pan American Health Organization, this document discusses the role of health technology assessment in improving healthcare efficiency, safety, and cost-effectiveness in developing countries.